Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21797755 | 1.00 | L3MBTL1 (0.33) | L3MBTL1NPC1ALDH1A1CASP3RAB9A | |
| Hydrochloric Acid SCHEMBL29540992 | 1.00 | L3MBTL1 (0.33) | L3MBTL1NPC1ALDH1A1CASP3RAB9A | |
| Hydrochloric Acid SCHEMBL29541165 | 0.86 | NPC1 (0.33) | L3MBTL1NPC1ALDH1A1CASP3RAB9A | |
| Hydrochloric Acid SCHEMBL19813107 | 0.84 | NR1H2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL29540788 | 0.83 | KIF11 (0.32) | ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL29541614 | 0.83 | KIF11 (0.32) | — | |
| Hydrochloric Acid SCHEMBL29540980 | 0.82 | ALDH1A1 (0.33) | ALDH1A1RAB9APLA2G1BATG4B | |
| Hydrochloric Acid SCHEMBL30393120 | 0.81 | NPC1 (0.32) | NPC1CASP3RAB9ASENP8SENP7 | |
| Hydrochloric Acid SCHEMBL30530999 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL29540795 | 0.81 | CES2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110494458-B | Alumoxane-activated metallocene catalysts | 博里利斯股份公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-110337455-B | Catalyst system for the production of polyethylene copolymers in a high temperature solution polymerization process | 博里利斯股份公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-110234665-B | Catalyst system for preparing polyethylene copolymers in high temperature solution polymerization process | 博里利斯股份公司 | 2022-05-24 | — | — | CN | disclosed |