Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | XDH | P47989 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | GRK6 | P43250 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1151183 | 1.00 | CYP1A2 (0.57) | CYP1A2XDHIDO1MAP4K4GSK3A | |
| Hydrochloric Acid SCHEMBL1296821 | 0.98 | CYP1A2 (0.56) | CYP1A2XDHIDO1MAP4K4GSK3A | |
| SCHEMBL13994269 | 0.84 | CYP1A2 (0.57) | CYP1A2XDHIDO1PDE4APDE4B | |
| SCHEMBL10353459 | 0.83 | CYP1A2 (0.74) | CYP1A2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1151830 | 0.80 | LMNA (0.61) | CYP1A2MAOBPDE4APDE4BPDE4C | |
| SCHEMBL15113272 | 0.79 | PGR (0.49) | CYP1A2PGRPDE4APDE4BPDE4C | |
| SCHEMBL24156317 | 0.78 | HPGDS (0.46) | CYP1A2XDHIDO1PDE4APDE4B | |
| SCHEMBL7298232 | 0.77 | CYP1A2 (0.65) | CYP1A2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30250881 | 0.76 | IDO1 (0.56) | XDHIDO1MAP4K4PGRMAOB | |
| SCHEMBL5269506 | 0.76 | L3MBTL1 (0.59) | XDHIDO1MAP4K4GSK3APGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114736191-B | Terpetinib intermediate and preparation method and application thereof | 上海工程技术大学 | 2023-08-08 | — | — | CN | claimed |
| CN-115583939-A | Synthesis method of Tepontinib intermediate | 苏州莱安医药化学技术有限公司 | 2023-01-10 | — | — | CN | claimed |
| CN-114736191-A | Tepritinib intermediate and preparation method and application thereof | 上海工程技术大学 | 2022-07-12 | — | — | CN | claimed |
| EP-4624472-A1 | DEGRADER INCLUDING NOVEL C-MET PROTEIN LIGAND AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | Innocure Therapeutics, Inc. (KR) | 2025-10-01 | — | — | EP | disclosed |
| CN-120118040-A | In terponinib intermediate and preparation method thereof | 苏州华先医药科技有限公司 | 2025-06-10 | — | — | CN | disclosed |
| CN-119684263-A | Synthetic method of terpetinib and key intermediate thereof | 苏州莱安医药化学技术有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-118084871-B | Compound for targeted degradation of c-Met protein and preparation method and application thereof | 中国药科大学 | 2024-07-09 | — | — | CN | disclosed |
| WO-2024112120-A1 | DEGRADER INCLUDING NOVEL C-MET PROTEIN LIGAND AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | 주식회사 이노큐어테라퓨틱스 | 2024-05-30 | — | — | WO | disclosed |
| CN-118084871-A | Compound for targeted degradation of c-Met protein and preparation method and application thereof | 中国药科大学 | 2024-05-28 | — | — | CN | disclosed |
| EP-4346829-A1 | COMPOUNDS FOR THE TREATMENT OF GLIOBLASTOMA | Merck Patent GmbH (DE) | 2024-04-10 | — | — | EP | disclosed |
| CN-116082309-B | Pyrimidine derivative 1D228 hydrochloride crystal form and preparation method and application thereof | 广东莱恩医药研究院有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-114736191-B | Terpetinib intermediate and preparation method and application thereof | 上海工程技术大学 | 2023-08-08 | — | — | CN | disclosed |
| CN-116332911-A | Co-amorphous substance of free base or hydrochloride of pyrimidine derivative 1D228 and dispersing agent, and preparation method and application thereof | 广东莱恩医药研究院有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-116082309-A | Pyrimidine derivative 1D228 hydrochloride crystal form and preparation method and application thereof | 广东莱恩医药研究院有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-114394957-B | Preparation method of MET inhibitor terpotinib hydrochloride | 武汉九州钰民医药科技有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-115583939-A | Synthesis method of Tepontinib intermediate | 苏州莱安医药化学技术有限公司 | 2023-01-10 | — | — | CN | disclosed |
| WO-2022253935-A1 | COMPOUNDS FOR THE TREATMENT OF GLIOBLASTOMA | MERCK PATENT GMBH (DE) | 2022-12-08 | — | — | WO | disclosed |
| CN-114736191-A | Tepritinib intermediate and preparation method and application thereof | 上海工程技术大学 | 2022-07-12 | — | — | CN | disclosed |
| CN-114394957-A | Preparation method of MET inhibitor terbacitinib hydrochloride | 武汉九州钰民医药科技有限公司 | 2022-04-26 | — | — | CN | disclosed |
| WO-2022063869-A2 | COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTIONS | MERCK PATENT GMBH (DE) | 2022-03-31 | — | — | WO | disclosed |