Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28359257 | 0.89 | ALDH1A1 (0.47) | EHMT2POLBALDH1A1KDM4ENFKB1 | |
| SCHEMBL29922643 | 0.89 | ALDH1A1 (0.47) | EHMT2POLBALDH1A1KDM4ENFKB1 | |
| SCHEMBL29552492 | 0.79 | SYK (0.46) | POLBNFKB1SYKMAPTLMNA | |
| SCHEMBL28362708 | 0.78 | DHODH (0.45) | POLBALDH1A1KDM4EGAAALOX15 | |
| SCHEMBL29552431 | 0.78 | SYK (0.48) | POLBALDH1A1GAANFKB1SYK | |
| SCHEMBL23486571 | 0.77 | ILK (0.56) | ALDH1A1GAAALOX15SYKSMN1; SMN2 | |
| SCHEMBL29552807 | 0.75 | SYK (0.41) | ALDH1A1SYKMAPTLMNAKMT2A | |
| SCHEMBL22609234 | 0.75 | ALDH1A1 (0.49) | POLBALDH1A1KDM4EGAASYK | |
| SCHEMBL29552337 | 0.75 | SYK (0.40) | POLBALDH1A1SYKMAPTLMNA | |
| SCHEMBL29551786 | 0.74 | SYK (0.44) | POLBALDH1A1SYKKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022032484-A1 | PYRIDAZINE-3-FORMAMIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 北京诺诚健华医药科技有限公司 | 2022-02-17 | — | — | WO | disclosed |