SCHEMBL2955256

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29885350	0.86	TOP2A (0.60)	MYCTOP2AIDO1MAOAMAOB
	SCHEMBL14367752	0.86	TOP2A (0.60)	MYCTOP2AIDO1MAOAMAOB
	SCHEMBL3401507	0.85	TOP2A (0.58)	MYCTOP2AIDO1MAOAMAOB
	SCHEMBL2961898	0.82	FTO (0.46)	TOP2AIDO1MAOAMAOBALDH1A1
	SCHEMBL440072	0.82	DHODH (0.49)	TOP2AIDO1MAOAMAOBALDH1A1
	SCHEMBL440239	0.82	JAK2 (0.51)	TOP2AIDO1MAOAMAOBALDH1A1
	SCHEMBL28926584	0.81	TOP2A (0.59)	TOP2AIDO1MAOAMAOBALDH1A1
	SCHEMBL496431	0.81	MAOB (0.49)	MYCTOP2AIDO1MAOAMAOB
	SCHEMBL206232	0.81	TOP2A (0.56)	TOP2AIDO1MAOAMAOBALDH1A1
	SCHEMBL121325	0.80	TOP2A (0.65)	TOP2AIDO1MAOAMAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.