Aniline

Aniline

SCHEMBL295550

C1CC[SiH2]OC1.Nc1ccccc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
CYP3A4 P08684 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
TAAR1 Q96RJ0 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPT P10636 4/20 0.30
MAOA P21397 4/20 0.30
ALDH1A1 P00352 2/20 0.30
CYP1A2 P05177 2/20 0.30
CYP2C9 P11712 2/20 0.30
CYP2C19 P33261 2/20 0.30
L3MBTL1 Q9Y468 2/20 0.30
MAOB P27338 2/20 0.30
HTT P42858 2/20 0.30
KDM4E B2RXH2 1/20 0.30
CYP2D6 P10635 1/20 0.30
MEN1 O00255 1/20 0.30
PKM P14618 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL14358032 0.83 ALDH1A1 (0.39) CYP3A4TDP1TAAR1HSD17B10ALDH1A1
Biphenyl SCHEMBL121313 0.83 ALDH1A1 (0.39) CYP3A4TDP1TAAR1HSD17B10ALDH1A1
Biphenyl SCHEMBL8599004 0.82 ALDH1A1 (0.38) CYP3A4TDP1TAAR1HSD17B10ALDH1A1
SCHEMBL9490191 0.81 ALDH1A1 (0.30) ALDH1A1
Toluene SCHEMBL9487580 0.80 LMNA (0.44) TSHRALOX12
Phenol SCHEMBL9243036 0.80 CA12 (0.44) TDP1MEN1KMT2A
Phenol SCHEMBL6858847 0.80 CA12 (0.44) TDP1MEN1KMT2A
Phenol SCHEMBL2420081 0.80 CA12 (0.44) TDP1MEN1KMT2A
Aminobenzoic Acid SCHEMBL28087886 0.79 TSHR (0.39) TSHRTDP1HSD17B10MAPTALDH1A1
SCHEMBL6924022 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5681679-A Overcoated electrophotographic imaging member with resilient charge transport layer XEROX CORPORATION (US) 1997-10-28 US claimed
EP-1744220-B1 Imaging Members XEROX CORP (US) 2012-08-22 EP disclosed
US-8211603-B2 Photoreceptor XEROX CORPORATION (US) 2012-07-03 US disclosed
EP-1808732-B1 Photoreceptor with Overcoat Layer XEROX CORP (US) 2012-03-14 EP disclosed
US-8034518-B2 Photoreceptor XEROX CORPORATION (US) 2011-10-11 US disclosed
US-8029956-B2 Photoreceptor with overcoat layer XEROX CORPORATION (US) 2011-10-04 US disclosed
US-8029957-B2 Photoreceptor with overcoat layer XEROX CORPORATION (US) 2011-10-04 US disclosed
EP-1887428-B1 Photoreceptor XEROX CORP (US) 2011-08-17 EP disclosed
US-7875411-B2 photographic and electrophotographic apparatus comprising substrates, charge generating layers, charge transport layers comprising N,N,N'N'-tetra(4-methylphenyl)-(1,1'-biphenyl)-4,4'-diamine and protective overcoatings, having improved rate of discharging XEROX CORPORATION (US) 2011-01-25 US disclosed
US-7759032-B2 Photoreceptor with overcoat layer XEROX CORPORATION (US) 2010-07-20 US disclosed
US-6107439-A MIXTURE COMPRISING AN OXIDIZED AND NON-OXIDIZED HOLE TRANSPRTING HYDROXY-FUNCTIONAL ARYL AMINE IN A CROSSLINKED POLYAMIDE MATRIX WHEREBY THE OXIDATION AND CROSSLINKING HAS BEEN SIMULTANEOUSLY CAUSED BY AN ACID XEROX CORPORATION (US) 2000-08-22 US disclosed
US-6103436-A A PHOTOCONDUCTIVE LAYER COMPRISING A HYDROXY FUNCTIONALIZED AROMATIC DIAMINE AND A HYDROXY FUNCTIONALIZED TRIARYLAMINE AND A CROSSLINKED POLYAMIDE MATRIX XEROX CORPORATION (US) 2000-08-15 US disclosed
US-6096470-A UNDRIED CHARGE TRANSPORT LAYER(CTL) OVER A CHARGE GENERATING LAYER; APPLYING OVERCOAT OF SECOND FILM FORMING POLYMER AND SOLVENT INSOLUBLE IN THE CTL MATERIALS, HEATING TO MIGRATE CTL SOLVENT THROUGH OVERCOAT, INCREASING HEAT TO DRY OVERCOAT XEROX CORPORATION (US) 2000-08-01 US disclosed
US-5976744-A ELECTROPHOTOGRAPHIC IMAGING MEMBER XEROX CORPORATION (US) 1999-11-02 US disclosed
US-5709974-A IMAGING MEMBER WITH SUPPORT CARRYING A CHARGE GENERATING LAYER, CHARGE TRANSPORT LAYER AND OVERCOATING LAYER XEROX CORPORATION (US) 1998-01-20 US disclosed
US-5702854-A Compositions and photoreceptor overcoatings containing a dihydroxy arylamine and a crosslinked polyamide XEROX CORPORATION (US) 1997-12-30 US disclosed
US-5681679-A Overcoated electrophotographic imaging member with resilient charge transport layer XEROX CORPORATION (US) 1997-10-28 US disclosed
US-5681679-A Overcoated electrophotographic imaging member with resilient charge transport layer XEROX CORPORATION (US) 1997-10-28 US disclosed
US-5670291-A Process for fabricating an electrophotographic imaging member XEROX CORPORATION (US) 1997-09-23 US disclosed
US-5230976-A Polymeric arylamine silane compounds and imaging members incorporating same XEROX CORPORATION (US) 1993-07-27 US disclosed