Biphenyl

Biphenyl

SCHEMBL8599004

C1CC[SiH2]OC1.N.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
GAA P10253 2/20 0.33
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP2E1 P05181 1/20 0.31
CYP2A6 P11509 1/20 0.31
CYP2B6 P20813 1/20 0.31
HRH3 Q9Y5N1 1/20 0.30
MAPK1 P28482 1/20 0.30
FAAH O00519 1/20 0.30
MGLL Q99685 1/20 0.30
NCOA3 Q9Y6Q9 1/20 0.30
ORAI1 Q96D31 1/20 0.30
ORAI2 Q96SN7 1/20 0.30
ORAI3 Q9BRQ5 1/20 0.30
TRPV6 Q9H1D0 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL121313 0.98 ALDH1A1 (0.39) ALDH1A1GAAMEN1POLBKMT2A
Biphenyl SCHEMBL14358032 0.98 ALDH1A1 (0.39) ALDH1A1GAAMEN1POLBKMT2A
Biphenyl SCHEMBL16579645 0.86 NOTUM (0.32) ALDH1A1NOTUM
SCHEMBL9490191 0.83 ALDH1A1 (0.30) ALDH1A1
Aniline SCHEMBL295550 0.82 TSHR (0.44) ALDH1A1MEN1KMT2ACYP1A2CYP3A4
Phenol SCHEMBL2420081 0.82 CA12 (0.44) MEN1KMT2ATDP1MMP3BCL2L1
Toluene SCHEMBL9487580 0.82 LMNA (0.44) ORAI1ORAI2ORAI3TRPV6
Phenol SCHEMBL9243036 0.82 CA12 (0.44) MEN1KMT2ATDP1MMP3BCL2L1
Phenol SCHEMBL6858847 0.82 CA12 (0.44) MEN1KMT2ATDP1MMP3BCL2L1
SCHEMBL6924022 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0822952-A1 POLYDIORGANOSILOXANE OLIGOUREA SEGMENTED COPOLYMERS AND A PROCESS FOR MAKING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-02-11 EP disclosed
WO-1996034030-A1 POLYDIORGANOSILOXANE OLIGOUREA SEGMENTED COPOLYMERS AND A PROCESS FOR MAKING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-10-31 WO disclosed