Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 3/20 | 0.44 |
| ▸ | DHPS | P49366 | 8/20 | 0.42 |
| ▸ | ACLY | P53396 | 4/20 | 0.40 |
| ▸ | NEK2 | P51955 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20727040 | 0.87 | KMO (0.43) | KMODHPSNEK2 | |
| SCHEMBL16036648 | 0.86 | NEK2 (0.40) | DHPSNEK2HSD17B10 | |
| SCHEMBL29556640 | 0.86 | NEK2 (0.40) | DHPSNEK2HSD17B10 | |
| SCHEMBL29556583 | 0.86 | NEK2 (0.40) | DHPSNEK2 | |
| SCHEMBL16035711 | 0.86 | NEK2 (0.40) | DHPSNEK2 | |
| SCHEMBL1397025 | 0.85 | PRKCZ (0.42) | PDE4DKDM4EALDH1A1HSD17B10 | |
| SCHEMBL27785181 | 0.84 | KMO (0.41) | KMODHPSNEK2KDM4EALDH1A1 | |
| SCHEMBL17745508 | 0.84 | TSPO (0.39) | KMODHPSACLYNEK2PDE4D | |
| SCHEMBL16075425 | 0.84 | KIF11 (0.45) | NEK2 | |
| SCHEMBL1397030 | 0.82 | DHPS (0.54) | KMODHPSNEK2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9763447-B2 | Safening 6-amino-2-(substituted phenyl)-5-substituted-4-pyrimidinecarboxylate herbicide injury on cereal crops | DOW AGROSCIENCES LLC (US) | 2017-09-19 | — | — | US | claimed |
| US-20160316745-A1 | SAFENING 6-AMINO-2-(SUBSTITUTED PHENYL)-5-SUBSTITUTED-4- PYRIMIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | CORTEVA AGRISCIENCE LLC | 2016-11-03 | — | — | US | claimed |
| US-9408387-B2 | Safening 6-amino-2-(substituted phenyl)-5-substituted-4-pyrimidinecarboxylate herbicide injury on cereal crops | DOW AGROSCIENCES LLC (US) | 2016-08-09 | — | — | US | claimed |
| EP-2493292-B1 | SAFENING 6-AMINO-2-(SUBSTITUTED PHENYL)-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | DOW AGROSCIENCES LLC (US) | 2016-05-18 | — | — | EP | claimed |
| US-8609592-B2 | 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2013-12-17 | — | — | US | claimed |
| CN-101784531-B | 2- (substituted phenyl) -6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylic acid derivatives and their use as herbicides | DOW AGROSCIENCES LLC | 2013-05-01 | — | — | CN | claimed |
| CN-102686106-A | Reducing injury to cereal crops from 6-amino-2- (substituted phenyl) -5-substituted-4-pyrimidinecarboxylic herbicides | DOW AGROSCIENCES LLC | 2012-09-19 | — | — | CN | claimed |
| EP-2493292-A1 | SAFENING 6-AMINO-2-(SUBSTITUTED PHENYL)-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | Dow AgroSciences LLC (US) | 2012-09-05 | — | — | EP | claimed |
| WO-2011059718-A1 | SAFENING 6-AMINO-2-(SUBSTITUTED PHENYL)-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | DOW AGROSCIENCES LLC (US) | 2011-05-19 | — | — | WO | claimed |
| US-20110105325-A1 | SAFENING 6-AMINO-2-(SUBSTITUTED PHENYL)-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | DOW AGROSCIENCES LLC | 2011-05-05 | — | — | US | claimed |
| US-9763447-B2 | Safening 6-amino-2-(substituted phenyl)-5-substituted-4-pyrimidinecarboxylate herbicide injury on cereal crops | DOW AGROSCIENCES LLC (US) | 2017-09-19 | — | — | US | disclosed |
| US-20160316745-A1 | SAFENING 6-AMINO-2-(SUBSTITUTED PHENYL)-5-SUBSTITUTED-4- PYRIMIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | CORTEVA AGRISCIENCE LLC | 2016-11-03 | — | — | US | disclosed |
| US-9408387-B2 | Safening 6-amino-2-(substituted phenyl)-5-substituted-4-pyrimidinecarboxylate herbicide injury on cereal crops | DOW AGROSCIENCES LLC (US) | 2016-08-09 | — | — | US | disclosed |
| EP-2493292-B1 | SAFENING 6-AMINO-2-(SUBSTITUTED PHENYL)-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | DOW AGROSCIENCES LLC (US) | 2016-05-18 | — | — | EP | disclosed |
| US-8609592-B2 | 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2013-12-17 | — | — | US | disclosed |
| WO-2009029735-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-03-05 | — | — | WO | disclosed |
| US-20090062125-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | CORTEVA AGRISCIENCE LLC | 2009-03-05 | — | — | US | disclosed |
| US-20090062125-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | CORTEVA AGRISCIENCE LLC | 2009-03-05 | — | — | US | disclosed |
| US-20090062125-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | CORTEVA AGRISCIENCE LLC | 2009-03-05 | — | — | US | disclosed |
| WO-2009029735-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105325-A1 | SAFENING 6-AMINO-2-(SUBSTITUTED PHENYL)-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | CASP6, CASP2, DHFR | KMO 274/4885DHPS 220/4885ACLY 1196/4885 |
| US-20160316745-A1 | SAFENING 6-AMINO-2-(SUBSTITUTED PHENYL)-5-SUBSTITUTED-4- PYRIMIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | CASP6, CASP2, DHFR | KMO 274/4885DHPS 220/4885ACLY 1196/4885 |
| US-20090062125-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, DDC, AADAC | KMO 186/4885DHPS 420/4885ACLY 951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.