Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.43 |
| ▸ | NEK2 | P51955 | 3/20 | 0.41 |
| ▸ | DHPS | P49366 | 4/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.38 |
| ▸ | RARA | P10276 | 2/20 | 0.36 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
| ▸ | RARG | P13631 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16075374 | 0.89 | SLC6A3 (0.43) | KMONEK2DHPSABCB1ABCC1 | |
| SCHEMBL29556640 | 0.87 | NEK2 (0.40) | NEK2DHPSABCB1ABCC1PDE4B | |
| SCHEMBL29556583 | 0.87 | NEK2 (0.40) | NEK2DHPSABCB1ABCC1PDE4B | |
| SCHEMBL16035711 | 0.87 | NEK2 (0.40) | NEK2DHPSABCB1ABCC1PDE4B | |
| SCHEMBL16036648 | 0.87 | NEK2 (0.40) | NEK2DHPSABCB1ABCC1PDE4B | |
| SCHEMBL1397142 | 0.87 | KMO (0.44) | KMONEK2DHPS | |
| SCHEMBL16075425 | 0.85 | KIF11 (0.45) | NEK2 | |
| SCHEMBL20727092 | 0.84 | KMO (0.46) | KMORARARARBRARGPDE4B | |
| SCHEMBL1396987 | 0.82 | DHPS (0.51) | NEK2DHPS | |
| SCHEMBL16075508 | 0.81 | PRKAB2 (0.38) | NEK2DHPSABCB1ABCC1PRKAB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3440938-A1 | 4-AMINO-6-(4-SUBSTITUTED-PHENYL)-PICOLINATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2019-02-13 | — | — | EP | disclosed |