Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7811941 | 1.00 | GABRA1 (0.39) | GABRA1GABRB2TSHRKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL27546472 | 0.95 | GABRA1 (0.36) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL7599684 | 0.83 | GABRA1 (0.35) | GABRA1GABRB2TSHRKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL6910241 | 0.79 | GABRA1 (0.35) | GABRA1GABRB2TSHRKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL27492991 | 0.79 | GABRA1 (0.32) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL4946925 | 0.78 | CYP1A2 (0.31) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29612304 | 0.78 | GABRA1 (0.34) | GABRA1GABRB2TSHRKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL7144896 | 0.78 | GABRA1 (0.34) | GABRA1GABRB2TSHRKDM4EMEN1 | |
| SCHEMBL27464020 | 0.77 | GABRA1 (0.36) | GABRA1GABRB2TSHRKDM4EMEN1 | |
| SCHEMBL27538533 | 0.77 | GABRA1 (0.36) | GABRA1GABRB2TSHRKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12110359-B2 | Continuous process for metallocene preliminary polymerization for gas-phase polymerization process | BRASKEM S.A. (BR) | 2024-10-08 | — | — | US | disclosed |
| EP-4370566-A1 | CONTINUOUS PROCESS FOR METALLOCENE PRELIMINARY POLYMERIZATION FOR GAS-PHASE POLYMERIZATION PROCESS | Braskem S.A. (BR) | 2024-05-22 | — | — | EP | disclosed |
| US-20230036349-A1 | CONTINUOUS PROCESS FOR METALLOCENE PRELIMINARY POLYMERIZATION FOR GAS-PHASE POLYMERIZATION PROCESS | BRASKEM S.A. (BR) | 2023-02-02 | — | — | US | disclosed |
| WO-2023285880-A1 | CONTINUOUS PROCESS FOR METALLOCENE PRELIMINARY POLYMERIZATION FOR GAS-PHASE POLYMERIZATION PROCESS | BRASKEM S.A. (BR) | 2023-01-19 | — | — | WO | disclosed |
| EP-3649185-B1 | ETHYLENE ALPHA-OLEFIN COPOLYMERS WITH MULTIMODAL COMONOMER DISTRIBUTIONS AND PROCESSES FOR OBTAINING THE SAME | BRASKEM SA (BR) | 2022-04-06 | — | — | EP | disclosed |