Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29565874 | 0.79 | GABRA1 (0.39) | GABRA1GABRB2TSHRKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL7811941 | 0.79 | GABRA1 (0.39) | GABRA1GABRB2TSHRKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL4237085 | 0.78 | SLC6A2 (0.32) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7144896 | 0.78 | GABRA1 (0.34) | GABRA1GABRB2TSHRKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL29612304 | 0.78 | GABRA1 (0.34) | GABRA1GABRB2TSHRKDM4EMEN1 | |
| SCHEMBL27538533 | 0.77 | GABRA1 (0.36) | GABRA1GABRB2TSHRKDM4EMEN1 | |
| SCHEMBL27464020 | 0.77 | GABRA1 (0.36) | GABRA1GABRB2TSHRKDM4EMEN1 | |
| SCHEMBL7027942 | 0.77 | GABRA1 (0.36) | GABRA1GABRB2TSHRKDM4EMEN1 | |
| Fluoride Ion SCHEMBL7640507 | 0.76 | GABRA1 (0.35) | GABRA1GABRB2TSHRKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL27546472 | 0.76 | GABRA1 (0.36) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790917-B2 | POLYMERIZING A VINYL COMPOUND IN PRESENCE OF A CATALYST OBTAINED BY COMBINING ORGANOTRANSITION METAL COMPOUND, AN ALUMINUM COMPUND OR ALUMOXANE AND A BORON COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-09-14 | — | — | US | disclosed |
| US-20020198340-A1 | Process for producing vinyl compound polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-26 | — | — | US | disclosed |