Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | CASP6 | P55212 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.53 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9786187 | 0.96 | DUSP5 (0.59) | KMT2AMEN1CASP6GFERDUSP5 | |
| Potassium Ion SCHEMBL10575064 | 0.91 | KDM4E (0.54) | KMT2AMEN1CASP6GFERDUSP5 | |
| SCHEMBL11701446 | 0.85 | LMNA (0.53) | KMT2AMEN1CASP6GFERDUSP5 | |
| SCHEMBL28623672 | 0.84 | DUSP5 (0.61) | KMT2AMEN1CASP6GFERDUSP5 | |
| SCHEMBL2264797 | 0.78 | KMT2A (0.58) | KMT2AMEN1CASP6GFERDUSP5 | |
| SCHEMBL29902411 | 0.78 | MEN1 (0.63) | KMT2AMEN1CASP6GFERGAA | |
| SCHEMBL9786190 | 0.78 | KMT2A (0.58) | KMT2AMEN1CASP6GFERDUSP5 | |
| SCHEMBL2951392 | 0.78 | KMT2A (0.58) | KMT2AMEN1CASP6GFERDUSP5 | |
| SCHEMBL9786185 | 0.77 | KMT2A (0.56) | KMT2AMEN1CASP6GFERDUSP5 | |
| Potassium SCHEMBL2956797 | 0.77 | KMT2A (0.56) | KMT2AMEN1CASP6GFERDUSP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772009-B2 | Room temperature phosphorescence apparatus and methods | SCR Research, LLC (US) | 2010-08-10 | — | — | US | disclosed |
| WO-2007061574-A2 | ROOM TEMPERATURE PHOSPHORESCENCE APPARATUS AND METHODS | SCA RESEARCH, LLC (US) | 2007-05-31 | — | — | WO | disclosed |
| US-20070117215-A1 | Room temperature phosphorescence apparatus and methods | POLYMER CONCEPTS TECHNOLOGIES PBY, INC. | 2007-05-24 | — | — | US | disclosed |