Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.82 |
| ▸ | MEN1 | O00255 | 5/20 | 0.82 |
| ▸ | F13A1 | P00488 | 1/20 | 0.72 |
| ▸ | TGM2 | P21980 | 1/20 | 0.72 |
| ▸ | TGM1 | P22735 | 1/20 | 0.72 |
| ▸ | ATM | Q13315 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1662361 | 0.86 | MAPT (0.74) | MAPTKMT2AMEN1F13A1TGM2 | |
| SCHEMBL1874408 | 0.84 | F13A1 (1.00) | MAPTF13A1TGM2TGM1ALDH1A1 | |
| SCHEMBL23217100 | 0.83 | MAPT (0.70) | MAPTKMT2AMEN1ATMALDH1A1 | |
| SCHEMBL4759272 | 0.82 | KMT2A (0.78) | MAPTKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL3300404 | 0.82 | ALDH1A1 (0.84) | MAPTKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL30513335 | 0.81 | SMN1; SMN2 (0.79) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL18711452 | 0.81 | KMT2A (0.76) | MAPTKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL4075002 | 0.81 | L3MBTL1 (1.00) | MAPTKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL4070839 | 0.80 | ALDH1A1 (0.84) | MAPTKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL616835 | 0.80 | ALDH1A1 (0.78) | MAPTKMT2AMEN1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759339-B2 | Hydroxysteroid dehydrogenase inhibitors | TAKEDA SAN DIEGO, INC. (US) | 2010-07-20 | — | — | US | claimed |
| EP-1866298-A2 | HYDROXYSTEROID DEHYDROGENASE INHIBITORS | Takeda San Diego, Inc. (US) | 2007-12-19 | — | — | EP | claimed |
| WO-2006105127-A2 | HYDROXYSTEROID DEHYDROGENASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2006-10-05 | — | — | WO | claimed |
| US-20060223829-A1 | Hydroxysteroid dehydrogenase inhibitors | TAKEDA SAN DIEGO, INC. | 2006-10-05 | — | — | US | claimed |
| CN-119330892-A | Benzenesulfonamide derivative and preparation method and application thereof | 天津科技大学 | 2025-01-21 | — | — | CN | disclosed |
| CN-116496292-A | Benzenesulfonamide derivative and preparation method and application thereof | 天津科技大学 | 2023-07-28 | — | — | CN | disclosed |
| US-7759339-B2 | Hydroxysteroid dehydrogenase inhibitors | TAKEDA SAN DIEGO, INC. (US) | 2010-07-20 | — | — | US | disclosed |
| US-7759339-B2 | Hydroxysteroid dehydrogenase inhibitors | TAKEDA SAN DIEGO, INC. (US) | 2010-07-20 | — | — | US | disclosed |
| EP-1866298-A2 | HYDROXYSTEROID DEHYDROGENASE INHIBITORS | Takeda San Diego, Inc. (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006105127-A2 | HYDROXYSTEROID DEHYDROGENASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2006-10-05 | — | — | WO | disclosed |
| US-20060223829-A1 | Hydroxysteroid dehydrogenase inhibitors | TAKEDA SAN DIEGO, INC. | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223829-A1 | Hydroxysteroid dehydrogenase inhibitors | HSD17B1, HSD17B3, HSD17B2 | MAPT 3168/4885KMT2A 3335/4885MEN1 2689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.