SCHEMBL29574162

SCHEMBL29574162

Cc1ccccc1C(=O)C1=NOC(Cc2ccccc2)C1

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
HTR2B P41595 1/20 0.45
MAPK14 Q16539 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29574378 0.86 LMNA (0.46) LMNA
SCHEMBL29573882 0.83
SCHEMBL892050 0.82 LMNA (0.53) LMNA
SCHEMBL29574351 0.80 VNN1 (0.46)
SCHEMBL892286 0.79 ALDH1A1 (0.58) CYP2C19
SCHEMBL29573823 0.78 LMNA (0.47) LMNA
SCHEMBL29575398 0.78 ACHE (0.47) LMNA
SCHEMBL29573827 0.78 RAB9A (0.44) LMNA
SCHEMBL29573887 0.75 PPARG (0.44)
SCHEMBL29574252 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108947924-B Preparation method and application of dihydroisoxazole benzophenone derivative and dihydroisoxazole benzophenone derivative 石河子大学 2022-05-10 CN claimed
CN-108947924-B Preparation method and application of dihydroisoxazole benzophenone derivative and dihydroisoxazole benzophenone derivative 石河子大学 2022-05-10 CN disclosed