Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 11/20 | 0.53 |
| ▸ | DRD2 | P14416 | 4/20 | 0.53 |
| ▸ | DRD5 | P21918 | 4/20 | 0.53 |
| ▸ | DRD3 | P35462 | 4/20 | 0.53 |
| ▸ | HTR1A | P08908 | 6/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29578483 | 0.97 | CHRM1 (0.53) | HTR7DRD2DRD5DRD3HTR1A | |
| SCHEMBL29577619 | 0.81 | HTR7 (0.48) | HTR7DRD2HTR1ACHRM1GRIN1 | |
| SCHEMBL11526850 | 0.80 | BMPR1B (0.48) | CHRM1USP2ALDH1A1 | |
| SCHEMBL29577669 | 0.80 | HRH1 (0.47) | HTR7DRD2DRD5DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL9095647 | 0.79 | DRD4 (0.60) | HTR7DRD2DRD3HTR1ACHRM1 | |
| SCHEMBL9096134 | 0.78 | DRD2 (0.62) | HTR7DRD2DRD5DRD3HTR1A | |
| SCHEMBL7824808 | 0.77 | MEN1 (0.42) | HTR7DRD2CHRM1USP2ALDH1A1 | |
| SCHEMBL8146689 | 0.77 | BMPR1B (0.47) | HTR7CHRM1USP2ALDH1A1 | |
| SCHEMBL17073872 | 0.77 | GRIN1 (0.57) | HTR7DRD2DRD5DRD3HTR1A | |
| SCHEMBL11529967 | 0.77 | BRD4 (0.55) | CHRM1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538038-B | 2-indolone ERR alpha inverse agonist and pharmaceutical composition and application thereof | 暨南大学 | 2022-05-20 | — | — | CN | disclosed |