SCHEMBL2958287

SCHEMBL2958287

COc1ccc(S(OS(=O)(=O)c2ccc(F)cc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.48
LMNA P02545 1/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ALDH1A1 P00352 2/20 0.45
PKM P14618 1/20 0.44
TUBB4A P04350 1/20 0.43
TUBB P07437 1/20 0.43
TUBA3C P0DPH7 1/20 0.43
TUBA1B P68363 1/20 0.43
TUBA4A P68366 1/20 0.43
TUBB4B P68371 1/20 0.43
TUBB3 Q13509 1/20 0.43
TUBB2A Q13885 1/20 0.43
TUBB8 Q3ZCM7 1/20 0.43
TUBA3E Q6PEY2 1/20 0.43
TUBA1A Q71U36 1/20 0.43
TUBA1C Q9BQE3 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2960247 0.94 PKM (0.50) STAT3LMNAHTTSMN1; SMN2TDP1
SCHEMBL5169176 0.92 HTT (0.53) LMNAHTTSMN1; SMN2TDP1L3MBTL1
SCHEMBL2964762 0.92 HTT (0.53) LMNAHTTSMN1; SMN2TDP1L3MBTL1
SCHEMBL450431 0.92 HTT (0.53) LMNAHTTSMN1; SMN2TDP1L3MBTL1
SCHEMBL2955282 0.89 KMT2A (0.49) ALDH1A1PKMFFAR1FFAR4HSD11B1
SCHEMBL3143801 0.86 LMNA (0.51) LMNAHTTSMN1; SMN2TDP1L3MBTL1
SCHEMBL759994 0.86 LMNA (0.51) LMNAHTTSMN1; SMN2TDP1L3MBTL1
SCHEMBL3137415 0.84 KMT2A (0.46) LMNAHTTSMN1; SMN2PKM
SCHEMBL1002297 0.84 KMT2A (0.46) LMNAHTTSMN1; SMN2PKM
SCHEMBL2960626 0.84 KMT2A (0.46) LMNAHTTSMN1; SMN2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7759045-B2 Chemically amplified positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-20 US disclosed
US-20090004601-A1 Chemically amplified positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-01 US disclosed
US-6893794-B2 Chemical amplification type positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-05-17 US disclosed
US-20040018445-A1 Chemical amplification type positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-01-29 US disclosed
US-20030068573-A1 Chemical amplification type positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-04-10 US disclosed