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Sugi Predict / Compounds / SCHEMBL29583545

SCHEMBL29583545

SCHEMBL29583545

CCN(CC)c1ccc2cc(-c3nc4ccccc4s3)c(=O)oc2c1.[In+3]

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PIK3CD O00329 1/20 0.64
▸ PIK3CB P42338 1/20 0.64
▸ CYP19A1 P11511 4/20 0.62
▸ MAPT P10636 11/20 0.61
▸ LMNA P02545 6/20 0.61
▸ MEN1 O00255 5/20 0.61
▸ HTT P42858 5/20 0.61
▸ KMT2A Q03164 5/20 0.61
▸ NPC1 O15118 4/20 0.61
▸ ATM Q13315 3/20 0.61
▸ USP2 O75604 3/20 0.61
▸ RAB9A P51151 3/20 0.61
▸ CASP1 P29466 2/20 0.61
▸ CASP7 P55210 2/20 0.61
▸ HBB P68871 2/20 0.61
▸ NPSR1 Q6W5P4 2/20 0.61
▸ TP53 P04637 1/20 0.61
▸ POLB P06746 1/20 0.61
▸ BRCA1 P38398 1/20 0.61
▸ PTK2B Q14289 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29360600 0.99 PIK3CD (0.65) PIK3CDPIK3CBCYP19A1MAPTLMNA
SCHEMBL5002101 0.99 PIK3CD (0.65) PIK3CDPIK3CBCYP19A1MAPTLMNA
SCHEMBL29362764 0.99 PIK3CD (0.65) PIK3CDPIK3CBCYP19A1MAPTLMNA
SCHEMBL38421 0.99 PIK3CD (0.65) PIK3CDPIK3CBCYP19A1MAPTLMNA
SCHEMBL29891568 0.98 PIK3CD (0.64) PIK3CDPIK3CBCYP19A1MAPTLMNA
SCHEMBL28829995 0.98 PIK3CD (0.64) PIK3CDPIK3CBCYP19A1MAPTLMNA
Coumarin SCHEMBL7203261 0.91 PIK3CD (0.57) PIK3CDPIK3CBCYP19A1MAPTLMNA
SCHEMBL1133687 0.91 PIK3CD (0.58) PIK3CDPIK3CBCYP19A1MAPTLMNA
SCHEMBL29696056 0.91 PIK3CD (0.58) PIK3CDPIK3CBCYP19A1MAPTLMNA
SCHEMBL12762289 0.90 PIK3CD (0.56) PIK3CDPIK3CBCYP19A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117384259-A Cell penetrating peptides based on influenza virus M2 proteins 中国医学科学院基础医学研究所 2024-01-12 — — CN claimed
CN-112912386-B Cell penetrating peptides based on influenza virus M2 proteins 中国医学科学院基础医学研究所 2023-10-20 — — CN claimed
CN-116855536-A Construct for real-time tracing of genomic spatial conformation and transcription products in living cells and uses thereof 生物岛实验室 2023-10-10 — — CN claimed
US-20220169680-A1 CELL-PENETRATING PEPTIDE BASED ON INFLUENZA VIRUS M2 PROTEIN INSTITUTE OF BASIC MEDICAL SCIENCES CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2022-06-02 — — US claimed
US-20260146063-A1 CYCLIC CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2026-05-28 — — US disclosed
US-20260125426-A1 CYCLIC CELL-PENETRATING PEPTIDES AND USES THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2026-05-07 — — US disclosed
US-20260070947-A1 CYCLIC CELL-PENETRATING PEPTIDE COMPOUNDS OHIO STATE INNOVATION FOUNDATION (US) 2026-03-12 — — US disclosed
US-20260070948-A1 CYCLIC CELL-PENETRATING PEPTIDES WITH CARGO OHIO STATE INNOVATION FOUNDATION (US) 2026-03-12 — — US disclosed
US-20260009759-A1 ANALYTE SENSOR DEXCOM, INC. (US) 2026-01-08 — — US disclosed
US-20260008816-A1 CYCLIC CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2026-01-08 — — US disclosed
US-20260008812-A1 CELL-PENETRATING PEPTIDE COMPOUNDS OHIO STATE INNOVATION FOUNDATION (US) 2026-01-08 — — US disclosed
US-20260008813-A1 CELL-PENETRATING PEPTIDE COMPOUNDS OHIO STATE INNOVATION FOUNDATION (US) 2026-01-08 — — US disclosed
US-11414455-B2 Toll-like receptor 2 ligands and methods of making and using thereof H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) 2022-08-16 — — US disclosed
US-20220214300-A1 MEMBRANE LAYERS FOR ANALYTE SENSORS DEXCOM, INC. (US) 2022-07-07 — — US disclosed
US-20220177523-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF ENTRADA THERAPEUTICS, INC. 2022-06-09 — — US disclosed
US-11351222-B2 Di-sulfide containing cell penetrating peptides and methods of making and using thereof OHIO STATE INNOVATION FOUNDATION (US) 2022-06-07 — — US disclosed
US-11352394-B2 Cyclic cell penetrating peptides comprising beta-hairpin motifs and methods of making and using thereof OHIO STATE INNOVATION FOUNDATION (US) 2022-06-07 — — US disclosed
US-20220169680-A1 CELL-PENETRATING PEPTIDE BASED ON INFLUENZA VIRUS M2 PROTEIN INSTITUTE OF BASIC MEDICAL SCIENCES CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2022-06-02 — — US disclosed
US-20220160819-A1 DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-05-26 — — US disclosed
US-11262326-B2 Membrane layers for analyte sensors DEXCOM, INC. (US) 2022-03-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11352394-B2 Cyclic cell penetrating peptides comprising beta-hairpin motifs and methods of making and using thereof VIP, LNPEP, IAPP PIK3CD 3805/4885PIK3CB 3591/4885CYP19A1 4815/4885
US-20260008816-A1 CYCLIC CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF SLC3A2, SPPL2B, SLC7A1 PIK3CD 2320/4885PIK3CB 1984/4885CYP19A1 4352/4885
US-20260008812-A1 CELL-PENETRATING PEPTIDE COMPOUNDS SLC38A7, SLC7A1, SLC6A7 PIK3CD 4497/4885PIK3CB 4719/4885CYP19A1 4244/4885
US-20260146063-A1 CYCLIC CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, SLC7A1, SLC6A15 PIK3CD 4347/4885PIK3CB 4529/4885CYP19A1 4748/4885
US-20260125426-A1 CYCLIC CELL-PENETRATING PEPTIDES AND USES THEREOF SLC7A1, TAP1, SLC7A5 PIK3CD 4317/4885PIK3CB 4586/4885CYP19A1 4436/4885
US-20220177523-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, LNPEP, TAP1 PIK3CD 3832/4885PIK3CB 3543/4885CYP19A1 4766/4885
US-20260070947-A1 CYCLIC CELL-PENETRATING PEPTIDE COMPOUNDS SLC7A1, SLC38A7, SLC6A19 PIK3CD 4366/4885PIK3CB 4630/4885CYP19A1 4570/4885
US-20220160819-A1 DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF IKBKE, IKBKB, SHARPIN PIK3CD 3453/4885PIK3CB 3110/4885CYP19A1 4143/4885
US-11414455-B2 Toll-like receptor 2 ligands and methods of making and using thereof TLR2, TLR3, TLR4 PIK3CD 2039/4885PIK3CB 1764/4885CYP19A1 4083/4885
US-20260070948-A1 CYCLIC CELL-PENETRATING PEPTIDES WITH CARGO SLC7A1, SLC38A7, SLC6A19 PIK3CD 4571/4885PIK3CB 4637/4885CYP19A1 4668/4885
US-11351222-B2 Di-sulfide containing cell penetrating peptides and methods of making and using thereof IKBKE, IKBKB, SHARPIN PIK3CD 3453/4885PIK3CB 3110/4885CYP19A1 4143/4885
US-11262326-B2 Membrane layers for analyte sensors MGAM, UGDH, UNG PIK3CD 1606/4885PIK3CB 1459/4885CYP19A1 3187/4885
US-20260008813-A1 CELL-PENETRATING PEPTIDE COMPOUNDS SLC7A1, SLC38A7, SLC6A19 PIK3CD 4622/4885PIK3CB 4808/4885CYP19A1 4194/4885
US-20260009759-A1 ANALYTE SENSOR EPCAM, SLC6A12, GJB2 PIK3CD 1600/4885PIK3CB 1898/4885CYP19A1 4224/4885
US-20220214300-A1 MEMBRANE LAYERS FOR ANALYTE SENSORS MGAM, UGDH, UNG PIK3CD 1606/4885PIK3CB 1459/4885CYP19A1 3187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.