SCHEMBL29584428

SCHEMBL29584428

NC(=O)c1ccc(C(=O)NCCN2CCN3Cc4[nH]c5ccccc5c4CC3C2)cc1

nearest known ligand 0.63

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ DRD3 P35462 1/20 0.61
▸ PRMT5 O14744 2/20 0.43
▸ WDR77 Q9BQA1 2/20 0.43
▸ HDAC1 Q13547 2/20 0.43
▸ HDAC6 Q9UBN7 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.42
▸ LMNA P02545 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ PLD2 O14939 2/20 0.41
▸ PLD1 Q13393 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biriperone SCHEMBL635469 0.76 DRD3 (1.00) DRD3
SCHEMBL11883126 0.67 DRD3 (0.50) DRD3KDM4EMAPT
SCHEMBL30969330 0.66 ALDH1A1 (0.71) HDAC1HDAC6KDM4E
SCHEMBL12244114 0.65 KDM4E (0.48) DRD3KDM4E
SCHEMBL29605727 0.65 CYP1A2 (0.74) HDAC1HDAC6KDM4E
SCHEMBL19139017 0.63 KDM4E (0.46) DRD3KDM4E
SCHEMBL10722398 0.63 HPGD (0.67) HDAC6KDM4EMAPT
SCHEMBL3065071 0.62 ADRA1A (0.45) DRD3KDM4E
SCHEMBL12727426 0.61 CYP19A1 (0.58) KDM4EMAPT
SCHEMBL1338592 0.61 CYP19A1 (0.68) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025085869-A1 IMPROVED HYDROGEL FOR DELIVERY OF PHARMACEUTICAL AGENTS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-04-24 — — WO disclosed
US-12208094-B2 Extended release, abuse deterrent dosage forms SpecGx LLC (US) 2025-01-28 — — US disclosed
US-20240009117-A1 ENHANCED UPTAKE TRANSMUCOSAL DRUG DELIVERY COMPOSITIONS AND METHODS OF USE PADAGIS ISRAEL PHARMACEUTICALS LTD. 2024-01-11 — — US disclosed
EP-3164117-B1 ABUSE DETERRENT IMMEDIATE RELEASE FORMULATIONS COMPRISING NON-CELLULOSE POLYSACCHARIDES SpecGx LLC (US) 2023-09-06 — — EP disclosed
US-11617712-B2 Abuse deterrent immediate release formulations comprising non-cellulose polysaccharides SpecGx LLC (US) 2023-04-04 — — US disclosed
US-20230079134-A1 EXTENDED RELEASE, ABUSE DETERRENT DOSAGE FORMS SUCAMPO PHARMA AMERICAS LLC 2023-03-16 — — US disclosed
US-11583493-B2 Abuse deterrent immediate release formulations comprising non-cellulose polysaccharides SpecGx LLC (US) 2023-02-21 — — US disclosed
US-11517521-B2 Abuse deterrent immediate release formulations comprising non-cellulose polysaccharides SpecGx LLC (US) 2022-12-06 — — US disclosed
US-11478426-B2 Abuse deterrent immediate release capsule dosage forms SpecGx LLC (US) 2022-10-25 — — US disclosed
US-11446293-B2 Extended release, abuse deterrent dosage forms SpecGx LLC (US) 2022-09-20 — — US disclosed
WO-2022098641-A1 ENHANCED UPTAKE TRANSMUCOSAL DRUG DELIVERY COMPOSITIONS AND METHODS OF USE PADAGIS ISRAEL PHARMACEUTICALS LTD. (US) 2022-05-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240009117-A1 ENHANCED UPTAKE TRANSMUCOSAL DRUG DELIVERY COMPOSITIONS AND METHODS OF USE SLC18A3, SLC10A2, SLC18A1 DRD3 2835/4885PRMT5 3417/4885WDR77 3915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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