Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 8/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | HRH2 | P25021 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR1E | P28566 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29589992 | 0.83 | TMEM97 (0.53) | BCL2MAP3K5TMEM97SIGMAR1HTR1A | |
| SCHEMBL29589768 | 0.78 | TMEM97 (0.57) | BCL2MAP3K5TMEM97SIGMAR1HTR1A | |
| SCHEMBL17890696 | 0.75 | BCL2 (1.00) | BCL2 | |
| SCHEMBL29589723 | 0.73 | BCL2 (0.52) | BCL2 | |
| SCHEMBL29589765 | 0.73 | BCL2 (0.49) | BCL2 | |
| SCHEMBL29589757 | 0.72 | BCL2 (0.42) | BCL2 | |
| SCHEMBL29589684 | 0.71 | BCL2 (0.51) | BCL2 | |
| SCHEMBL29590813 | 0.71 | BCL2 (0.55) | BCL2 | |
| SCHEMBL29590949 | 0.71 | NAMPT (0.42) | BCL2 | |
| SCHEMBL29589831 | 0.71 | OPRM1 (0.43) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109456324-B | Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-04-22 | — | — | CN | disclosed |