Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNMT | Q14749 | 3/20 | 0.71 |
| ▸ | NNMT | P40261 | 6/20 | 0.62 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.58 |
| ▸ | DPP4 | P27487 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.58 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.58 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.58 |
| ▸ | GAPDH | P04406 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.58 |
| ▸ | STAT6 | P42226 | 1/20 | 0.58 |
| ▸ | PI4KA | P42356 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.58 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29598730 | 0.85 | TYMP (0.57) | GNMTNNMT | |
| SCHEMBL19302866 | 0.84 | GNMT (0.60) | GNMT | |
| SCHEMBL19302805 | 0.84 | — | — | |
| Adenosine SCHEMBL11656001 | 0.83 | ADORA3 (0.78) | GNMTDOT1LDPP4MEN1SLC28A1 | |
| SCHEMBL19302871 | 0.83 | GNMT (0.59) | GNMTNNMT | |
| SCHEMBL11519694 | 0.80 | NNMT (0.76) | GNMTNNMTDOT1LDPP4MEN1 | |
| SCHEMBL14696727 | 0.79 | NNMT (0.78) | GNMTNNMTDOT1LDPP4MEN1 | |
| SCHEMBL16486489 | 0.79 | EHMT1 (0.75) | NNMTDOT1LDPP4MEN1SLC28A1 | |
| SCHEMBL10766543 | 0.79 | EHMT1 (0.75) | NNMTDOT1LDPP4MEN1SLC28A1 | |
| SCHEMBL5972642 | 0.78 | DOT1L (0.76) | NNMTDOT1LDPP4MEN1SLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250197344-A1 | COMPOUNDS AND METHODS FOR TREATMENT OF BACTERIAL INFECTIONS | VICTORIA LINK LIMITED (NZ) | 2025-06-19 | — | — | US | disclosed |
| US-12258304-B2 | Compounds and methods for treatment of bacterial infections | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2025-03-25 | — | — | US | disclosed |
| US-11948662-B2 | Metabolite, annotation, and gene integration system and method | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-04-02 | — | — | US | disclosed |
| US-20220234995-A1 | COMPOUNDS AND METHODS FOR TREATMENT OF BACTERIAL INFECTIONS | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2022-07-28 | — | — | US | disclosed |
| US-20220127311-A1 | CELL FACTORIES FOR IMPROVED PRODUCTION OF COMPOUNDS AND PROTEINS DEPENDENT ON IRON SULFUR CLUSTERS | BIOSYNTIA APS (DK) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250197344-A1 | COMPOUNDS AND METHODS FOR TREATMENT OF BACTERIAL INFECTIONS | FNTB, PGLS, FUT6 | GNMT 468/4885NNMT 469/4885DOT1L 4139/4885 |
| US-12258304-B2 | Compounds and methods for treatment of bacterial infections | FNTB, PGLS, FUT6 | GNMT 468/4885NNMT 469/4885DOT1L 4139/4885 |
| US-20220234995-A1 | COMPOUNDS AND METHODS FOR TREATMENT OF BACTERIAL INFECTIONS | FNTB, PGLS, FUT6 | GNMT 468/4885NNMT 469/4885DOT1L 4139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.