Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601196 | 0.86 | HDAC1 (0.43) | TLR8TLR7POLBL3MBTL1CYP2C9 | |
| SCHEMBL29601395 | 0.80 | HDAC1 (0.43) | — | |
| SCHEMBL29601423 | 0.77 | ALDH1A1 (0.36) | POLB | |
| SCHEMBL29601224 | 0.69 | HDAC1 (0.58) | — | |
| SCHEMBL29601461 | 0.68 | SQOR (0.34) | POLBL3MBTL1 | |
| SCHEMBL29601167 | 0.64 | ALDH1A1 (0.36) | POLB | |
| SCHEMBL29601499 | 0.64 | GAA (0.35) | L3MBTL1CYP2C9 | |
| SCHEMBL24846612 | 0.63 | CYP1A2 (0.62) | — | |
| SCHEMBL29601247 | 0.62 | SLC29A1 (0.39) | POLB | |
| SCHEMBL16513142 | 0.62 | CTSL (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997089-A1 | CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF | University Of Virginia Patent Foundation (US) | 2022-05-18 | — | — | EP | claimed |
| EP-3997089-A1 | CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF | University Of Virginia Patent Foundation (US) | 2022-05-18 | — | — | EP | disclosed |