Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601846 | 0.85 | L3MBTL1 (0.36) | GAAALDH1A1KDM4EHPGDHTT | |
| SCHEMBL29601199 | 0.81 | ALDH1A1 (0.34) | GAAALDH1A1KDM4EHPGDHTT | |
| SCHEMBL29601427 | 0.68 | L3MBTL1 (0.38) | GAAALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL21628864 | 0.58 | PTGER4 (0.47) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL21628803 | 0.57 | HPGDS (0.44) | ALDH1A1KMT2A | |
| SCHEMBL24124968 | 0.56 | LMNA (0.71) | GAAALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL22724722 | 0.56 | RAB9A (0.62) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL27584263 | 0.56 | GAA (0.42) | GAAALDH1A1KDM4EHPGDHTT | |
| SCHEMBL9999838 | 0.55 | MAPT (0.83) | GAAALDH1A1HPGDHTTKMT2A | |
| SCHEMBL8737929 | 0.55 | LMNA (0.87) | GAAALDH1A1KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997089-A1 | CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF | University Of Virginia Patent Foundation (US) | 2022-05-18 | — | — | EP | claimed |
| EP-3997089-A1 | CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF | University Of Virginia Patent Foundation (US) | 2022-05-18 | — | — | EP | disclosed |