Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SQOR | Q9Y6N5 | 3/20 | 0.39 |
| ▸ | PNP | P00491 | 7/20 | 0.39 |
| ▸ | TK1 | P04183 | 1/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5347874 | 0.87 | PNP (0.50) | KMT2ASQORPNPTK1HPRT1 | |
| SCHEMBL7094400 | 0.77 | TK1 (0.50) | KMT2APNPTK1HPRT1MEN1 | |
| SCHEMBL27569986 | 0.75 | TK1 (0.46) | KMT2APNPTK1HPRT1MEN1 | |
| SCHEMBL5468657 | 0.74 | GSK3B (0.63) | GSK3B | |
| SCHEMBL29601253 | 0.73 | HDAC1 (0.44) | SQORGSK3B | |
| SCHEMBL1404481 | 0.73 | GAA (0.38) | KMT2AGAAPNPTK1HPRT1 | |
| SCHEMBL29601208 | 0.72 | HDAC1 (0.43) | SQORGSK3B | |
| SCHEMBL29601213 | 0.71 | HDAC1 (0.42) | SQORGSK3B | |
| SCHEMBL7165218 | 0.71 | SQOR (0.45) | KMT2AGAASQORPNPHPRT1 | |
| SCHEMBL29601164 | 0.70 | HDAC1 (0.35) | KMT2AGAASQORGSK3BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993000099-A2 | USE OF PYRIMIDINE AND PURINE NUCLEOSIDES FOR THE PROPHYLAXIS AND/OR TREATMENT OF INFECTIONS CAUSED BY ADENOVIRUSES | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 1993-01-07 | — | — | WO | disclosed |