Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601570 | 0.82 | P2RX7 (0.54) | ALDH1A1MEN1KMT2AHPGDPOLB | |
| SCHEMBL29601170 | 0.78 | ALDH1A1 (0.35) | ALDH1A1TSHRP2RX7 | |
| SCHEMBL29601519 | 0.77 | CA1 (0.37) | ALDH1A1MEN1KMT2APOLBP2RX7 | |
| SCHEMBL29601245 | 0.71 | YTHDC1 (0.47) | ALDH1A1KMT2AHPGDTSHRSMN1; SMN2 | |
| SCHEMBL183167 | 0.71 | YTHDC1 (0.47) | ALDH1A1KMT2AHPGDTSHRSMN1; SMN2 | |
| SCHEMBL29601397 | 0.70 | P2RX7 (0.35) | P2RX7 | |
| SCHEMBL29601682 | 0.66 | ALDH3A1 (0.47) | ALDH1A1P2RX7KDM4E | |
| SCHEMBL5756666 | 0.66 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AHPGDPOLB | |
| SCHEMBL29601293 | 0.66 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ATSHRRAB9A | |
| SCHEMBL3425599 | 0.65 | ADORA2A (0.39) | ALDH1A1KMT2AHPGDTSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997089-A1 | CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF | University Of Virginia Patent Foundation (US) | 2022-05-18 | — | — | EP | disclosed |