Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20473299 | 1.00 | CTSS (0.41) | CTSSCTSKCTSLHDAC4HDAC1 | |
| SCHEMBL20473295 | 0.92 | CTSS (0.44) | CTSSCTSKCTSLHDAC4HDAC1 | |
| SCHEMBL30374901 | 0.90 | AAK1 (0.49) | CTSSCTSKHDAC4HDAC1AAK1 | |
| SCHEMBL29042833 | 0.90 | AAK1 (0.49) | CTSSCTSKHDAC4HDAC1AAK1 | |
| SCHEMBL20473276 | 0.89 | SMN1; SMN2 (0.47) | MAPTALDH1A1GAASMN1; SMN2PPARG | |
| SCHEMBL19006724 | 0.89 | SMN1; SMN2 (0.47) | MAPTALDH1A1GAASMN1; SMN2PPARG | |
| SCHEMBL21272080 | 0.87 | AAK1 (0.51) | CTSSCTSKCTSLAAK1 | |
| SCHEMBL21272077 | 0.87 | AAK1 (0.51) | CTSSCTSKCTSLAAK1 | |
| SCHEMBL20473233 | 0.85 | CCR9 (0.45) | CTSSCTSKCTSLHDAC4HDAC1 | |
| SCHEMBL19006591 | 0.85 | CCR9 (0.45) | CTSSCTSKCTSLHDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119192183-A | Benzodiazepines class of compounds and uses thereof | 中国药科大学 | 2024-12-27 | — | — | CN | disclosed |
| US-20230416258-A1 | BENZODIAZEPINE COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2023-12-28 | — | — | US | disclosed |
| CN-116507628-A | Novel benzodiazepine compound, preparation method and application thereof | 中国药科大学 | 2023-07-28 | — | — | CN | disclosed |
| CN-110418791-B | Injection composition comprising benzodiazepine compound and method for preparing the same | 四川科伦博泰生物医药股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114456171-A | Benzodiazepine medicine for sedation and hypnosis, preparation method and application thereof | 中国药科大学 | 2022-05-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230416258-A1 | BENZODIAZEPINE COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF | GABRA4, GABRA1, GABRA5 | CTSS 3607/4885CTSK 4502/4885CTSL 2211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.