SCHEMBL29605671

SCHEMBL29605671

CC(=O)OC[C@H]1CC[C@H](n2cnc3c(Nc4cccc(O)c4)ncnc32)O1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRKAB2 O43741 1/20 0.67
▸ PRKAG1 P54619 1/20 0.67
▸ PRKAA2 P54646 1/20 0.67
▸ PRKAA1 Q13131 1/20 0.67
▸ PRKAG3 Q9UGI9 1/20 0.67
▸ PRKAG2 Q9UGJ0 1/20 0.67
▸ PRKAB1 Q9Y478 1/20 0.67
▸ ADORA3 P0DMS8 1/20 0.42
▸ ADORA1 P30542 1/20 0.42
▸ DNPH1 O43598 1/20 0.42
▸ CCNA2 P20248 2/20 0.41
▸ CDK2 P24941 2/20 0.41
▸ CDK5 Q00535 2/20 0.41
▸ CDK5R1 Q15078 2/20 0.41
▸ BCHE P06276 1/20 0.41
▸ LMNA P02545 2/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ GLA P06280 1/20 0.41
▸ PMP22 Q01453 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23982207 0.86 PRKAB2 (0.52) PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
SCHEMBL19236026 0.84 PRKAB2 (0.73) PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
SCHEMBL19236034 0.80 PRKAB2 (1.00) PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
SCHEMBL29611296 0.80 PRKAB2 (1.00) PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
SCHEMBL716606 0.80 PRKAB2 (1.00) PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
SCHEMBL10001662 0.80 PRKAB2 (1.00) PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
SCHEMBL9121390 0.80 ALDH1A1 (0.45) PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
SCHEMBL22452057 0.80 ADORA3 (0.55) ADORA3ADORA1ADORA2AADORA2B
SCHEMBL9587879 0.80 ADORA3 (0.46) PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
SCHEMBL24436940 0.80 ADORA3 (0.55) ADORA3ADORA1ADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4599048-A1 COMPOSITIONS AND METHODS FOR SMALL MOLECULE BASED EXPANSION OF PLURIPOTENT STEM CELLS Trailhead Biosystems Inc. (US) 2025-08-13 — — EP claimed
EP-4569090-A2 METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS Trailhead Biosystems Inc. (US) 2025-06-18 — — EP claimed
CN-119654404-A Methods and compositions for producing oligodendrocyte progenitor cells 特雷尔赫德生物系统股份有限公司 2025-03-18 — — CN claimed
WO-2024112806-A1 GENERATION AND USE OF EPIGENETIC MAPS FOR DRUG DISCOVERY MOONWALK BIOSCIENCES, INC. (US) 2024-05-30 — — WO claimed
WO-2024063818-A9 METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS TRAILHEAD BIOSYSTEMS INC. (US) 2024-05-23 — — WO claimed
US-20240117302-A1 COMPOSITIONS AND METHODS FOR SMALL MOLECULE BASED EXPANSION OF PLURIPOTENT STEM CELLS TRAILHEAD BIOSYSTEMS INC. 2024-04-11 — — US claimed
WO-2024076758-A1 COMPOSITIONS AND METHODS FOR SMALL MOLECULE BASED EXPANSION OF PLURIPOTENT STEM CELLS TRAILHEAD BIOSYSTEMS INC. (US) 2024-04-11 — — WO claimed
WO-2024063818-A2 METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS TRAILHEAD BIOSYSTEMS INC. (US) 2024-03-28 — — WO claimed
US-20240043798-A1 METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS TRAILHEAD BIOSYSTEMS INC. 2024-02-08 — — US claimed
CN-116200330-A Method for down-regulating MAPK8 expression to induce reprogramming of cells into mammary epithelial cells 广西壮族自治区人民医院 2023-06-02 — — CN claimed
EP-4615869-A1 COMBINATION THERAPY COMPRISING BISPECIFIC ANTIBODIES COMPRISING AN NRP1 BINDING DOMAIN Pinetree Therapeutics, Inc. (US) 2025-09-17 — — EP disclosed
EP-4599048-A1 COMPOSITIONS AND METHODS FOR SMALL MOLECULE BASED EXPANSION OF PLURIPOTENT STEM CELLS Trailhead Biosystems Inc. (US) 2025-08-13 — — EP disclosed
EP-4569090-A2 METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS Trailhead Biosystems Inc. (US) 2025-06-18 — — EP disclosed
WO-2025103336-A1 USE OF TRIACETYL-3-HYDROXYPHENYLADENOSINE IN PREPARATION OF MOTION SIMULATION DRUG 中国医学科学院药物研究所 2025-05-22 — — WO disclosed
CN-119654404-A Methods and compositions for producing oligodendrocyte progenitor cells 特雷尔赫德生物系统股份有限公司 2025-03-18 — — CN disclosed
CN-112979734-B Crystal form of triacetyl-3-hydroxy phenyl adenosine, preparation method and application thereof 北京谷神生命健康科技有限公司 2024-01-02 — — CN disclosed
CN-116200330-A Method for down-regulating MAPK8 expression to induce reprogramming of cells into mammary epithelial cells 广西壮族自治区人民医院 2023-06-02 — — CN disclosed
EP-3466433-B1 TRIACETYL-3-HYDROXYL PHENYL ADENOSINE FOR USE IN TREATING ACUTE VASCULAR INFLAMMATIONS BEIJING GUSHEN LIFE HEALTH TECH CO LTD (CN) 2022-09-07 — — EP disclosed
US-11324768-B2 Applications of triacetyl-3-hydroxyl phenyl adenosine in treating vascular inflammations or improving vascular endothelium functions JIANGSU TASLY DIYI PHARMACEUTICALS CO., LTD. (CN) 2022-05-10 — — US disclosed
CN-114377136-A Combined medicine for treating hyperlipemia and its use 中国医学科学院药物研究所 2022-04-22 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11324768-B2 Applications of triacetyl-3-hydroxyl phenyl adenosine in treating vascular inflammations or improving vascular endothelium functions LIPG, ADORA2A, VCAM1 PRKAB2 95/4885PRKAG1 128/4885PRKAA2 299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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