SCHEMBL2960739

SCHEMBL2960739

CC(C)COCCOCCOC(=O)CCCCC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.46
TSHR P16473 3/20 0.40
MAPT P10636 1/20 0.40
ALDH1A1 P00352 2/20 0.39
PAM P19021 2/20 0.39
NPC1 O15118 1/20 0.38
LMNA P02545 3/20 0.37
RECQL P46063 1/20 0.36
TLR2 O60603 1/20 0.36
EPHX2 P34913 1/20 0.36
DNM1 Q05193 1/20 0.36
CYP3A4 P08684 1/20 0.36
ATM Q13315 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
NFKB1 P19838 1/20 0.35
PMP22 Q01453 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2964522 0.98 DGKA (0.47) DGKATSHRMAPTALDH1A1PAM
SCHEMBL2960370 0.92 ALDH1A1 (0.42) DGKATSHRMAPTALDH1A1PAM
SCHEMBL2956543 0.90 ADRA2A (0.38) DGKATSHRMAPTALDH1A1NPC1
SCHEMBL2956618 0.88 ADRA2A (0.39) DGKATSHRMAPTALDH1A1NPC1
SCHEMBL1480557 0.87 MAPT (0.51) DGKATSHRMAPTALDH1A1PAM
SCHEMBL9972407 0.86 DGKA (0.54) DGKATSHRALDH1A1PAMNPC1
SCHEMBL10783946 0.86 DGKA (0.54) DGKATSHRALDH1A1PAMNPC1
SCHEMBL10789977 0.85 DGKA (0.49) DGKATSHRMAPTALDH1A1PAM
SCHEMBL17909259 0.84 TSHR (0.46) TSHRALDH1A1LMNATLR2TDP1
SCHEMBL17909058 0.84 TSHR (0.46) TSHRALDH1A1LMNATLR2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2392314-B1 OILY HAIR COSMETIC KOKYU ALCOHOL KOGYO CO LTD (JP) 2019-08-14 EP disclosed
US-8562957-B2 Oily hair cosmetics KOKYU ALCOHOL KOGYO CO., LTD. (JP) 2013-10-22 US disclosed
US-20100203003-A1 Oily Hair Cosmetics KOKYU ALCOHOL KOGYO CO., LTD. (JP) 2010-08-12 US disclosed
US-7766978-B2 Acidic hair dyeing method KOKYU ALCOHOL KOGYO CO., LTD. (JP) 2010-08-03 US disclosed
US-20090100609-A1 ACIDIC HAIR DYE COMPOSITION KOKYU ALCOHOL KOGYO CO., LTD. (JP) 2009-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090100609-A1 ACIDIC HAIR DYE COMPOSITION H1-0, MRM1, H1-4 DGKA 2503/4885TSHR 3886/4885MAPT 4627/4885
US-20100203003-A1 Oily Hair Cosmetics H1-0, H1-2, H1-3 DGKA 781/4885TSHR 1973/4885MAPT 4080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.