Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.43 |
| ▸ | UGT1A3 | P35503 | 1/20 | 0.43 |
| ▸ | UGT1A8 | Q9HAW9 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2959650 | 0.87 | MEN1 (0.35) | JUNUGT1A1UGT1A3UGT1A8MAOB | |
| SCHEMBL2957000 | 0.82 | MEN1 (0.47) | MAOBLMNAALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL1100519 | 0.76 | MAOB (0.50) | JUNUGT1A1UGT1A3UGT1A8MAOB | |
| SCHEMBL2965162 | 0.74 | PTGS2 (0.42) | MAOBALDH1A1NPC1SMN1; SMN2MAPT | |
| SCHEMBL9002504 | 0.74 | HPGD (0.59) | JUNUGT1A1UGT1A3UGT1A8MAOB | |
| SCHEMBL1100077 | 0.73 | PARP10 (0.43) | JUNUGT1A1UGT1A3UGT1A8MAOB | |
| SCHEMBL2968672 | 0.73 | PTGS2 (0.36) | MAOBLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL2967202 | 0.71 | MAOB (0.36) | MAOBLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL12316318 | 0.69 | PARP10 (0.55) | MAOBPARP10ALDH1A1NPC1RAB9A | |
| SCHEMBL1376229 | 0.69 | MAOB (0.56) | MAOBPARP10ALDH1A1MAPTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1445249-B1 | NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2012-11-07 | — | — | EP | disclosed |
| US-7772285-B2 | Benzophenone derivatives or salts thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |
| US-20050113400-A1 | Inhibitors of transcription factor AP-1; autoimmune diseases; rheumatoid arthritis; high safety and excellent pharmacokinetics in vivo | SHUNICHI SHIOZAWA (JP) | 2005-05-26 | — | — | US | disclosed |
| EP-1445249-A1 | NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113400-A1 | Inhibitors of transcription factor AP-1; autoimmune diseases; rheumatoid arthritis; high safety and excellent pharmacokinetics in vivo | SP1, AP1G1, JUN | JUN 3/4885UGT1A1 1244/4885UGT1A3 2640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.