SCHEMBL1100519

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1100768	0.80	CA9 (0.62)	MAOBMAOAKMT2AKDM4EALDH1A1
	SCHEMBL28135822	0.80	MAOB (0.52)	MAOBMAOAKMT2AKDM4EALDH1A1
	SCHEMBL2961235	0.76	JUN (0.43)	MAOBJUNUGT1A1UGT1A3UGT1A8
	SCHEMBL1108352	0.76	ALDH1A1 (0.59)	MAOBKMT2AKDM4EALDH1A1GLA
	SCHEMBL16674816	0.75	MAOA (0.68)	MAOBMAOAKMT2AKDM4EALDH1A1
	SCHEMBL28918559	0.74	KDM4E (0.61)	MAOBMAOAKMT2AKDM4EALDH1A1
	SCHEMBL9002504	0.74	HPGD (0.59)	MAOBJUNUGT1A1UGT1A3UGT1A8
	SCHEMBL1100077	0.74	PARP10 (0.43)	MAOBJUNUGT1A1UGT1A3UGT1A8
	7-Cyclohexyloxycoumarin SCHEMBL14802688	0.74	MAOA (0.67)	MAOBMAOAKMT2AKDM4EALDH1A1
	7-Cyclohexyloxycoumarin SCHEMBL28918560	0.73	KDM4E (0.63)	MAOBMAOAKMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.