Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
| ▸ | WRN | Q14191 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 2/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598859 | 0.82 | BRD4 (0.35) | CREBBPBRD4PARP1NR1H4PTAFR | |
| SCHEMBL27519275 | 0.81 | PRCP (0.41) | KMT2AKDM4E | |
| SCHEMBL27482270 | 0.81 | PRCP (0.41) | KMT2AKDM4E | |
| SCHEMBL6523433 | 0.72 | NR1H4 (0.33) | CREBBPBRD4PARP1NR1H4PTAFR | |
| SCHEMBL27816247 | 0.72 | PNMT (0.44) | CREBBPBRD4PARP1PTAFRNPC1 | |
| SCHEMBL29612355 | 0.71 | BRD4 (0.45) | CREBBPBRD4PARP1 | |
| SCHEMBL27500822 | 0.69 | HTR7 (0.44) | BRD4LMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28930335 | 0.67 | ALDH1A1 (0.41) | HSD11B1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5917138 | 0.67 | CD44 (0.38) | KMT2AMEN1LMNAKDM4EALDH1A1 | |
| SCHEMBL24522126 | 0.66 | TSHR (0.48) | CREBBPBRD4NR1H4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199274-B2 | Preparation of substituted indenes | BASELL POLYOLEFINE GMBH (DE) | 2007-04-03 | — | — | US | disclosed |
| US-20050256344-A1 | Preparation of substituted indenes | BASELL POLYOLEFINE GMBH (DE) | 2005-11-17 | — | — | US | disclosed |
| EP-1554233-A1 | PREPARATION OF SUBSTITUTED INDENES | Basell Polyolefine GmbH (DE) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004037756-A1 | PREPARATION OF SUBSTITUTED INDENES | BASELL POLYOLEFINE GMBH (DE) | 2004-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256344-A1 | Preparation of substituted indenes | CYP1A2, CYP1B1, DHPS | CREBBP 3239/4885BRD4 2293/4885TRPV1 4317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.