SCHEMBL2961306

SCHEMBL2961306

CCCCCCCCCCCCCCCC(CC=O)CCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
TSHR P16473 2/20 0.44
ADH1B P00325 2/20 0.44
ADH1C P00326 2/20 0.44
ADH1A P07327 2/20 0.44
ADH4 P08319 2/20 0.44
ADH7 P40394 2/20 0.44
FAAH O00519 2/20 0.40
TRPV1 Q8NER1 1/20 0.40
MAPT P10636 2/20 0.38
TRPA1 O75762 1/20 0.38
DDAH1 O94760 1/20 0.38
GAPDH P04406 1/20 0.38
GPR84 Q9NQS5 3/20 0.38
FDPS P14324 3/20 0.38
FFAR1 O14842 1/20 0.38
EPHX1 P07099 1/20 0.37
LCK P06239 1/20 0.36
PPARD Q03181 1/20 0.36
ZDHHC20 Q5W0Z9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7733731 1.00 LMNA (0.46) LMNATSHRADH1BADH1CADH1A
SCHEMBL9263689 1.00 LMNA (0.46) LMNATSHRADH1BADH1CADH1A
SCHEMBL3850489 1.00 LMNA (0.46) LMNATSHRADH1BADH1CADH1A
SCHEMBL3847166 1.00 LMNA (0.46) LMNATSHRADH1BADH1CADH1A
SCHEMBL3841827 1.00 LMNA (0.46) LMNATSHRADH1BADH1CADH1A
SCHEMBL276625 0.98 LMNA (0.43) LMNATSHRADH1BADH1CADH1A
SCHEMBL5076605 0.96 LMNA (0.50) LMNATSHRADH1BADH1CADH1A
SCHEMBL16023957 0.96 LMNA (0.50) LMNATSHRADH1BADH1CADH1A
SCHEMBL5075482 0.96 LMNA (0.50) LMNATSHRADH1BADH1CADH1A
SCHEMBL22465774 0.96 LMNA (0.50) LMNATSHRADH1BADH1CADH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7754862-B2 Multi-chromophoric AZO pyridone colorants XEROX CORPORATION (US) 2010-07-13 US disclosed
US-7381253-B2 Multi-chromophoric azo pyridone colorants XEROX CORPORATION (US) 2008-06-03 US disclosed
US-20080071051-A1 MULTI-CHROMOPHORIC AZO PYRIDONE COLORANTS XEROX CORPORATION (US) 2008-03-20 US disclosed
EP-1375610-B1 Phase change inks containing dimeric azo pyridone colorants XEROX CORP (US) 2007-04-04 EP disclosed
EP-1375599-B1 Dimeric azo pyridone colorants XEROX CORP (US) 2006-10-04 EP disclosed
US-20060117991-A1 Phase change inks; piezoelectric printing XEROX CORPORATION 2006-06-08 US disclosed
US-6755902-B2 YELLOW DYE; THERMAL STABILITY; LIGHTFASTNESS; SOLUBILITY; SHARP DURABLE IMAGES; NONCLOGGING XEROX CORPORATION 2004-06-29 US disclosed
US-6713614-B2 PHASE CHANGE INKS XEROX CORPORATION 2004-03-30 US disclosed
US-6696552-B2 AMIDATION BETWEEN PRIMARY AMINE AND ESTER HAVING ELECTRON WITHDRAWING FUNCTIONALITY; CYCLIZATION WITH KETO ESTER XEROX CORPORATION 2004-02-24 US disclosed
US-20040010058-A1 DIMERIC AZO PYRIDONE COLORANTS XEROX CORPORATION 2004-01-15 US disclosed
US-20040007155-A1 Phase change inks containing azo pyridone colorants XEROX CORPORATION 2004-01-15 US disclosed
US-20040006234-A1 PROCESS FOR PREPARING SUBSTITUTED PYRIDONE COMPOUNDS XEROX CORPORATION 2004-01-08 US disclosed
EP-1375610-A1 Phase change inks containing dimeric azo pyridone colorants Xerox Corporation (US) 2004-01-02 EP disclosed
EP-1375599-A1 Dimeric azo pyridone colorants Xerox Corporation (US) 2004-01-02 EP disclosed
US-6663703-B1 Nonsettling hot melt color materials and carriers comprising stearyl stearamide, the reaction product of dimer acid, ethylene diamine and stearic acid or mixtures, used in ink jets printers, having colorfastness, heat and photostability XEROX CORPORATION 2003-12-16 US disclosed
US-6590082-B1 Color materials used as inks in phase change recording and dyeing of textiles, high spectral emmitance chromogens, electronics, optical and color filters XEROX CORPORATION 2003-07-08 US disclosed
US-6576747-B1 Reacting alkylenediol and isatoic anhydride in presence of 1,4-diazabicyclo(2.2.2)octane and/or N,N,N*,N*-tetramethylenediamine; heating, decyclization, salt formation XEROX CORPORATION 2003-06-10 US disclosed
US-6576748-B1 Diazotizing dianiline compound; salt formation, coupling, desalting; reaction with pyridone or dipyridone compound XEROX CORPORATION 2003-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060117991-A1 Phase change inks; piezoelectric printing RB1, CDKN1A, RCC1 LMNA 1205/4885TSHR 4483/4885ADH1B 4107/4885
US-20040006234-A1 PROCESS FOR PREPARING SUBSTITUTED PYRIDONE COMPOUNDS PDXK, DPYD, RRM2B LMNA 1206/4885TSHR 2092/4885ADH1B 74/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.