Ether

Ether

SCHEMBL2961472

CCOCC.O=C(O)CCC(=O)OCCO

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
MGLL Q99685 1/20 0.41
ADRA2A P08913 1/20 0.41
ADRA1A P35348 1/20 0.41
EGLN1 Q9GZT9 2/20 0.39
MAPT P10636 1/20 0.39
BLM P54132 1/20 0.39
KDM6B O15054 1/20 0.39
KDM5C P41229 1/20 0.39
PHF8 Q9UPP1 1/20 0.39
KDM2A Q9Y2K7 1/20 0.39
DGKA P23743 1/20 0.38
LMNA P02545 3/20 0.37
TSHR P16473 1/20 0.36
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36
PAM P19021 2/20 0.35
HTR2C P28335 1/20 0.35
ALKBH5 Q6P6C2 1/20 0.35
SUCNR1 Q9BXA5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL2960823 0.96 ALDH1A1 (0.40) ALDH1A1MGLLADRA2AADRA1AEGLN1
Ether SCHEMBL2964119 0.92 MGLL (0.40) ALDH1A1MGLLADRA2AADRA1AEGLN1
Ether SCHEMBL3022252 0.92 MGLL (0.37) ALDH1A1MGLLADRA2AADRA1AEGLN1
Ether SCHEMBL2962820 0.89 DGKA (0.40) ALDH1A1MGLLADRA2AADRA1AEGLN1
Ether SCHEMBL2962357 0.89 DGKA (0.48) ALDH1A1MGLLDGKATSHRPAM
SCHEMBL683877 0.88 LMNA (0.45) ALDH1A1MGLLADRA2AADRA1AEGLN1
Di(Hydroxyethyl)Ether SCHEMBL21225172 0.87 TSHR (0.48) ALDH1A1MGLLMAPTDGKATSHR
Ether SCHEMBL12980650 0.86 DGKA (0.44) ALDH1A1ADRA2AADRA1AEGLN1MAPT
Ether SCHEMBL2959979 0.86 DGKA (0.38) ALDH1A1MGLLADRA2AADRA1AEGLN1
Ether SCHEMBL2962330 0.86 DGKA (0.46) ALDH1A1MGLLDGKATSHRPAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7766978-B2 Acidic hair dyeing method KOKYU ALCOHOL KOGYO CO., LTD. (JP) 2010-08-03 US disclosed
US-20090100609-A1 ACIDIC HAIR DYE COMPOSITION KOKYU ALCOHOL KOGYO CO., LTD. (JP) 2009-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090100609-A1 ACIDIC HAIR DYE COMPOSITION H1-0, MRM1, H1-4 ALDH1A1 81/4885MGLL 3278/4885ADRA2A 3928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.