Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 3/20 | 0.45 |
| ▸ | PGR | P06401 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29615293 | 1.00 | KIF11 (0.45) | KIF11ARPGRPIK3CACYP11B1 | |
| SCHEMBL29615348 | 0.85 | SCN9A (0.39) | KIF11ARPGRPIK3CAAAK1 | |
| SCHEMBL20577865 | 0.85 | SCN9A (0.39) | KIF11ARPGRPIK3CAAAK1 | |
| SCHEMBL7271245 | 0.82 | AURKA (0.60) | PIK3CAAAK1AURKATTKAURKB | |
| SCHEMBL10460598 | 0.82 | CYP1A2 (0.40) | ARPGRCYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL3967559 | 0.78 | KIF11 (0.49) | KIF11ARCYP11B1CYP11B2DGAT1 | |
| SCHEMBL20577702 | 0.77 | NR3C1 (0.51) | KIF11PGRCYP11B2 | |
| SCHEMBL29615607 | 0.77 | NR3C1 (0.51) | KIF11PGRCYP11B2 | |
| SCHEMBL12427758 | 0.75 | ERN1 (0.42) | KIF11PIK3CAAURKATTKAURKB | |
| SCHEMBL12427700 | 0.75 | MAP4K4 (0.42) | PIK3CAAURKATTKAURKBINCENP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602807-B | Heterocyclic sulfonamide derivatives and drugs containing the same | EA制药株式会社 | 2022-05-13 | — | — | CN | disclosed |
| EP-3412664-B1 | HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE CONTAINING SAME | EA PHARMA CO LTD (JP) | 2022-03-30 | — | — | EP | disclosed |
| US-10584116-B2 | Heterocyclic sulfonamide derivative and medicine containing same | EA PHARMA CO., LTD. (JP) | 2020-03-10 | — | — | US | disclosed |
| US-20190023699-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE CONTAINING SAME | EA PHARMA CO., LTD. (JP) | 2019-01-24 | — | — | US | disclosed |
| EP-3412664-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE CONTAINING SAME | EA Pharma Co., Ltd. (JP) | 2018-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190023699-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE CONTAINING SAME | TRPA1, TRPV1, TRPV2 | KIF11 4552/4885AR 887/4885PGR 3133/4885 |
| US-10584116-B2 | Heterocyclic sulfonamide derivative and medicine containing same | TRPA1, TRPV1, TRPV2 | KIF11 4552/4885AR 887/4885PGR 3133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.