Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | RET | P07949 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24512062 | 0.70 | CES1 (0.35) | METAP2SIGMAR1CYP3A4SLC6A2LMNA | |
| SCHEMBL6337844 | 0.64 | PTAFR (0.41) | NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL28294184 | 0.64 | ALDH1A1 (0.43) | SIGMAR1LMNANPC1RAB9AMAPT | |
| SCHEMBL2874924 | 0.63 | CES1 (0.43) | SIGMAR1TSHRPARP1 | |
| SCHEMBL29370356 | 0.63 | CES1 (0.43) | SIGMAR1TSHRPARP1 | |
| SCHEMBL4313725 | 0.63 | ALDH1A1 (0.48) | METAP2CYP3A4LMNACYP1A2CYP2D6 | |
| SCHEMBL4436441 | 0.63 | CES1 (0.43) | SIGMAR1TSHRNPC1RAB9APARP1 | |
| SCHEMBL11503302 | 0.63 | MPO (0.57) | SIGMAR1CYP3A4SLC6A2LMNACYP1A2 | |
| SCHEMBL5489164 | 0.63 | SIGMAR1 (0.46) | SIGMAR1HTR6 | |
| SCHEMBL28294223 | 0.61 | SIGMAR1 (0.45) | SIGMAR1SLC6A2LMNACYP1A2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022123336-A1 | CHROMENO [4,3-B] QUINOLINE COMPOUNDS AND THEIR SYNTHESIS BY USING SILICOTUNGSTIC ACID [H4SIW12O40] | HEGDE SUBRAMANYA GOPAL (IN) | 2022-06-16 | — | — | WO | disclosed |