Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | PTAFR | P25105 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | RET | P07949 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24512368 | 0.78 | MAOB (0.34) | MIFSLC6A2LMNACYP1A2CHRM2 | |
| SCHEMBL24511863 | 0.76 | ALDH1A1 (0.33) | MIFCYP3A4SLC6A2LMNACYP1A2 | |
| SCHEMBL24512095 | 0.72 | — | — | |
| SCHEMBL29615670 | 0.70 | METAP2 (0.36) | RAB9ANPC1CYP3A4SLC6A2LMNA | |
| SCHEMBL8885671 | 0.69 | CES1 (0.47) | CES1RAB9ANPC1MIFLMNA | |
| SCHEMBL29952458 | 0.65 | ESR1 (0.54) | CES1RAB9ANPC1PARP1MAPT | |
| SCHEMBL4268656 | 0.65 | CES1 (0.47) | CES1MIFPARP1ESR1PKM | |
| SCHEMBL29615759 | 0.65 | CES1 (0.47) | CES1MIFPARP1ESR1PKM | |
| SCHEMBL2063760 | 0.65 | ESR1 (0.54) | CES1RAB9ANPC1PARP1MAPT | |
| SCHEMBL4271075 | 0.65 | LMNA (0.42) | CES1RAB9ANPC1CYP3A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022123336-A1 | CHROMENO [4,3-B] QUINOLINE COMPOUNDS AND THEIR SYNTHESIS BY USING SILICOTUNGSTIC ACID [H4SIW12O40] | HEGDE SUBRAMANYA GOPAL (IN) | 2022-06-16 | — | — | WO | disclosed |
| WO-2022123336-A1 | CHROMENO [4,3-B] QUINOLINE COMPOUNDS AND THEIR SYNTHESIS BY USING SILICOTUNGSTIC ACID [H4SIW12O40] | HEGDE SUBRAMANYA GOPAL (IN) | 2022-06-16 | — | — | WO | disclosed |