Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | RET | P07949 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9235448 | 0.85 | SIGMAR1 (0.50) | MPOSIGMAR1CES1 | |
| SCHEMBL5614129 | 0.80 | SIGMAR1 (0.53) | MPOSIGMAR1HTT | |
| SCHEMBL7837577 | 0.80 | SIGMAR1 (0.46) | MPOSIGMAR1CES1G6PC1CYP2A6 | |
| SCHEMBL29446311 | 0.80 | SIGMAR1 (0.46) | MPOSIGMAR1CES1G6PC1CYP2A6 | |
| SCHEMBL5489164 | 0.80 | SIGMAR1 (0.46) | MPOSIGMAR1CES1G6PC1CYP2A6 | |
| SCHEMBL28424372 | 0.80 | SIGMAR1 (0.46) | MPOSIGMAR1CES1G6PC1CYP2A6 | |
| SCHEMBL6825529 | 0.80 | SIGMAR1 (0.46) | MPOSIGMAR1CES1G6PC1CYP2A6 | |
| SCHEMBL9379776 | 0.80 | SIGMAR1 (0.46) | MPOSIGMAR1CES1G6PC1CYP2A6 | |
| SCHEMBL20824984 | 0.79 | SIGMAR1 (0.43) | MPOSIGMAR1CES1HTR6CYP1A2 | |
| SCHEMBL6552816 | 0.79 | HTR6 (0.53) | MPOCES1CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137419-A | FROM AN INDENE OR DIHYDRONAPHTHALENE | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1979-01-30 | — | — | US | disclosed |