Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 7/20 | 0.59 |
| ▸ | F2 | P00734 | 4/20 | 0.57 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29463733 | 0.91 | RAMP3 (0.61) | OPRD1OPRM1 | |
| SCHEMBL29463770 | 0.91 | RAMP3 (0.61) | OPRD1OPRM1 | |
| SCHEMBL31151670 | 0.85 | NTSR1 (0.60) | NTSR1F2NTSR2OPRD1 | |
| SCHEMBL30906513 | 0.85 | RAMP3 (0.55) | NTSR1F2OPRD1OPRM1 | |
| SCHEMBL29376302 | 0.84 | OPRM1 (0.64) | NTSR1F2OPRD1OPRM1 | |
| SCHEMBL30625026 | 0.84 | OPRM1 (0.64) | NTSR1F2OPRD1OPRM1 | |
| SCHEMBL29365606 | 0.84 | KEAP1 (0.56) | NTSR1F2NTSR2OPRD1 | |
| SCHEMBL29884130 | 0.83 | OPRM1 (0.61) | NTSR1OPRD1OPRM1 | |
| SCHEMBL31331967 | 0.83 | NMUR2 (0.65) | F2OPRD1 | |
| SCHEMBL29422997 | 0.83 | NMUR2 (0.65) | F2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11351268-B2 | FGF21 C-terminal peptide optimization | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2022-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11351268-B2 | FGF21 C-terminal peptide optimization | FGF23, FGFR1, FGFR3 | NTSR1 138/4885F2 3497/4885NTSR2 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.