SCHEMBL30852867

SCHEMBL30852867

CC(C)(C)OC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1)C(N)=O

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CAPN1 P07384 6/20 0.41
▸ CTSB P07858 1/20 0.41
▸ PLG P00747 3/20 0.40
▸ PLAT P00750 2/20 0.40
▸ DPP4 P27487 3/20 0.39
▸ FAP Q12884 1/20 0.39
▸ DPP8 Q6V1X1 1/20 0.39
▸ DPP9 Q86TI2 1/20 0.39
▸ DPP7 Q9UHL4 1/20 0.39
▸ GRB2 P62993 1/20 0.37
▸ OPRM1 P35372 1/20 0.37
▸ VHL P40337 1/20 0.36
▸ F2 P00734 1/20 0.36
▸ F10 P00742 1/20 0.36
▸ PRSS1 P07477 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29468837 0.91 KMT2A (0.41) DPP4FAPDPP8DPP9DPP7
SCHEMBL30972553 0.89 KMT2A (0.42) DPP4FAPDPP8DPP9DPP7
SCHEMBL29616517 0.86 CAPN1 (0.51) CAPN1CTSBPLGPLATDPP4
SCHEMBL30852860 0.84 CAPN1 (0.48) CAPN1CTSBGRB2OPRM1
SCHEMBL2194423 0.83 CAPN1 (0.48) CAPN1CTSBPLGPLATDPP4
SCHEMBL21519838 0.83 CAPN1 (0.48) CAPN1CTSBPLGPLATDPP4
SCHEMBL2184762 0.83 CAPN1 (0.48) CAPN1CTSBPLGPLATDPP4
SCHEMBL29468849 0.83 REN (0.45) GRB2F2
SCHEMBL30800860 0.82 DPP4 (0.44) CAPN1CTSBPLGPLATDPP4
SCHEMBL30800861 0.81 DPP4 (0.43) CAPN1CTSBPLGPLATDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4598938-A2 PEPTIDES FOR INCRETIN SYNTHESIS Eli Lilly and Company (US) 2025-08-13 — — EP disclosed
WO-2024077149-A2 PEPTIDES FOR INCRETIN SYNTHESIS ELI LILLY AND COMPANY (US) 2024-04-11 — — WO disclosed
Send feedback