Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29616987 | 0.81 | ADORA2A (0.47) | LMNASLC29A1MAPTMEN1KMT2A | |
| SCHEMBL23388290 | 0.75 | HSP90AA1 (0.57) | CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6280404 | 0.72 | PKM (0.49) | MAPTALDH1A1 | |
| SCHEMBL29616953 | 0.71 | ADORA2A (0.44) | LMNASLC29A1MEN1KMT2A | |
| SCHEMBL9982974 | 0.70 | RECQL (0.54) | LMNAMAPTGAATSHRHPGD | |
| SCHEMBL30135342 | 0.70 | RECQL (0.54) | LMNAMAPTGAATSHRHPGD | |
| SCHEMBL5905969 | 0.70 | BLM (0.38) | MAPTGAATSHRHPGDMEN1 | |
| SCHEMBL6281357 | 0.69 | NR3C1 (0.40) | MAPTGAATSHRHPGDNPC1 | |
| SCHEMBL6274939 | 0.69 | LMNA (0.45) | LMNAMAPTNR3C1PGRAR | |
| SCHEMBL16418006 | 0.69 | BRD4 (0.43) | LMNABRD4MAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022107044-A1 | PREVENTION AND/OR TREATMENT OF CNS DISORDERS | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-05-27 | — | — | WO | disclosed |