Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8349013 | 0.80 | TSHR (0.45) | TSHRALDH1A1RAB9AKDM4EAPOBEC3A | |
| SCHEMBL8859640 | 0.80 | ALDH1A1 (0.45) | TSHRALDH1A1RAB9AKDM4EAPOBEC3A | |
| SCHEMBL2961735 | 0.80 | TSHR (0.45) | TSHRALDH1A1RAB9AKDM4EAPOBEC3A | |
| SCHEMBL13176644 | 0.79 | NFE2L2 (0.41) | TSHRALDH1A1RAB9AKDM4EAPOBEC3A | |
| SCHEMBL17151526 | 0.79 | MMP1 (0.46) | TSHRALDH1A1RAB9AKDM4ETP53 | |
| SCHEMBL17682919 | 0.78 | TSHR (0.43) | TSHRALDH1A1RAB9AKDM4EAPOBEC3A | |
| SCHEMBL13816225 | 0.78 | TSHR (0.43) | TSHRALDH1A1RAB9AKDM4EAPOBEC3A | |
| SCHEMBL26539118 | 0.78 | ALDH1A1 (0.43) | TSHRALDH1A1RAB9AKDM4EAPOBEC3A | |
| SCHEMBL903372 | 0.76 | RAB9A (0.41) | TSHRALDH1A1RAB9AKDM4EAPOBEC3A | |
| SCHEMBL8349679 | 0.76 | RAB9A (0.41) | TSHRALDH1A1RAB9AKDM4EAPOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345904-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | Chiesi Farmaceutici S.p.a. (IT) | 2018-07-11 | — | — | EP | disclosed |