Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6283140 | 0.91 | MAPT (0.49) | PTGS2ALDH1A1MAPTPKMHTT | |
| SCHEMBL7210133 | 0.91 | PTGS2 (0.62) | PTGS2ALDH1A1MAPTPKMHTT | |
| SCHEMBL3026019 | 0.88 | PTGS2 (0.46) | PTGS2ALDH1A1MAPTPKMHTT | |
| SCHEMBL7215254 | 0.86 | PTGS2 (0.78) | PTGS2ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL3026333 | 0.86 | PTGS2 (0.78) | PTGS2ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL5314020 | 0.84 | CHRNA7 (0.60) | PTGS2 | |
| SCHEMBL3026121 | 0.84 | CHRNA7 (0.60) | PTGS2 | |
| SCHEMBL3034062 | 0.83 | PTGS2 (0.46) | PTGS2ALDH1A1MAPTPKMHTT | |
| SCHEMBL3031646 | 0.83 | CA12 (0.58) | PTGS2ALDH1A1MAPTPKMHTT | |
| SCHEMBL2320353 | 0.83 | POLB (0.65) | ALDH1A1MAPTHTTPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9657037-B2 | Pyrrole compounds with silicon incorporation | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-05-23 | — | — | US | disclosed |
| US-9657037-B2 | Pyrrole compounds with silicon incorporation | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-05-23 | — | — | US | disclosed |
| US-9657037-B2 | Pyrrole compounds with silicon incorporation | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-05-23 | — | — | US | disclosed |
| US-20160115181-A1 | NOVEL PYRROLE COMPOUNDS WITH SILICON INCORPORATION | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-04-28 | — | — | US | disclosed |
| US-20160115181-A1 | NOVEL PYRROLE COMPOUNDS WITH SILICON INCORPORATION | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-04-28 | — | — | US | disclosed |
| US-20160115181-A1 | NOVEL PYRROLE COMPOUNDS WITH SILICON INCORPORATION | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-04-28 | — | — | US | disclosed |
| US-7763602-B2 | Pyrrole derivatives as antimycobacterial compounds | LUPIN LIMITED (IN) | 2010-07-27 | — | — | US | disclosed |
| US-7691837-B2 | Pyrrole derivatives as antimycobacterial compounds | LUPIN LIMITED (IN) | 2010-04-06 | — | — | US | disclosed |
| US-20080242676-A1 | PYRROLE DERIVATIVES AS ANTIMYCOBACTERIAL COMPOUNDS | LUPIN LIMITED (IN) | 2008-10-02 | — | — | US | disclosed |
| EP-1857442-A2 | Novel antimycobacterial compounds | Lupin Limited (IN) | 2007-11-21 | — | — | EP | disclosed |
| US-20050107370-A1 | Pyrrole derivatives as antimycobacterial compounds | LUPIN LIMITED (IN) | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160115181-A1 | NOVEL PYRROLE COMPOUNDS WITH SILICON INCORPORATION | PYCR1, MIF, PGLS | PTGS2 1056/4885ALDH1A1 3109/4885MAPT 2240/4885 |
| US-20080242676-A1 | PYRROLE DERIVATIVES AS ANTIMYCOBACTERIAL COMPOUNDS | PGLS, SDHA, SDHB | PTGS2 1573/4885ALDH1A1 369/4885MAPT 931/4885 |
| US-20050107370-A1 | Pyrrole derivatives as antimycobacterial compounds | PGLS, SDHA, SDHB | PTGS2 1573/4885ALDH1A1 369/4885MAPT 931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.