Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29619573 | 0.79 | SLC27A2 (0.46) | HTR6LMNAKMT2APOLBMEN1 | |
| SCHEMBL28515905 | 0.79 | SLC27A2 (0.46) | HTR6LMNAKMT2APOLBMEN1 | |
| SCHEMBL28522164 | 0.77 | TP53 (0.42) | HTR6LMNAKMT2APOLBMEN1 | |
| SCHEMBL29619574 | 0.76 | HCRTR1 (0.46) | HTR6KMT2APOLBMEN1CYP1A2 | |
| SCHEMBL28528531 | 0.74 | LMNA (0.42) | CES1LMNAKMT2APOLBMEN1 | |
| SCHEMBL29619616 | 0.72 | LMNA (0.40) | LMNAKMT2APOLBMEN1CYP1A2 | |
| SCHEMBL29619591 | 0.70 | ALDH1A1 (0.39) | HTR6KMT2AMEN1 | |
| SCHEMBL28526734 | 0.69 | LMNA (0.42) | HTR6LMNAKMT2APOLBMEN1 | |
| SCHEMBL29622128 | 0.68 | PDE4A (0.43) | BCHECES1CYP1A2CYP2C19 | |
| SCHEMBL28519633 | 0.66 | KMT2A (0.40) | LMNAKMT2APOLBMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022082817-A1 | 3-THREE-MEMBERED SPIROOXINDOLE DERIVATIVE SYNTHESIZING METHOD | 苏州大学 | 2022-04-28 | — | — | WO | disclosed |