Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.38 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23295193 | 1.00 | MRGPRX4 (0.41) | MRGPRX4NPC1PTGER1S1PR5CYP4F2 | |
| SCHEMBL23213368 | 0.94 | MRGPRX4 (0.38) | MRGPRX4NPC1PTGER1S1PR5CYP4F2 | |
| SCHEMBL29619704 | 0.84 | SLC6A9 (0.45) | MRGPRX4NPC1PTGER1S1PR5LIPE | |
| SCHEMBL29619701 | 0.84 | SLC6A9 (0.42) | MRGPRX4NPC1PTGER1CYP4F2CYP4A11 | |
| SCHEMBL23209843 | 0.84 | SLC6A9 (0.42) | MRGPRX4NPC1PTGER1CYP4F2CYP4A11 | |
| SCHEMBL23210176 | 0.84 | SLC6A9 (0.45) | MRGPRX4NPC1PTGER1S1PR5LIPE | |
| SCHEMBL31357720 | 0.82 | LTA4H (0.40) | MRGPRX4NPC1PTGER1S1PR5CYP4F2 | |
| SCHEMBL23212925 | 0.82 | SLC6A9 (0.43) | MRGPRX4NPC1PTGER1LIPEMAPT | |
| SCHEMBL23213167 | 0.81 | KEAP1 (0.43) | MRGPRX4MAPTLMNA | |
| SCHEMBL23210255 | 0.80 | SGMS2 (0.48) | LIPEMAPTMAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119390705-A | 5-Oxa-2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-114555606-B | 5-Oxa-2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-114555606-A | 5-oxa-2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2022-05-27 | — | — | CN | disclosed |