Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360083 | 0.87 | LMNA (0.47) | LMNAMAPK1HTTRAB9AKIF11 | |
| SCHEMBL850429 | 0.86 | KIF11 (0.57) | LMNAMAPK1HTTRAB9AKIF11 | |
| SCHEMBL29620952 | 0.86 | KIF11 (0.57) | LMNAMAPK1HTTRAB9AKIF11 | |
| Hydrochloric Acid SCHEMBL31439018 | 0.85 | KIF11 (0.56) | LMNAMAPK1HTTRAB9AKIF11 | |
| SCHEMBL16104820 | 0.83 | LMNA (0.51) | LMNAMAPK1HTTRAB9AKIF11 | |
| SCHEMBL11977452 | 0.81 | LMNA (0.53) | LMNAMAPK1HTTRAB9AKIF11 | |
| SCHEMBL12491995 | 0.79 | ACE2 (0.53) | LMNAMAPK1HTTRAB9AKIF11 | |
| SCHEMBL18671808 | 0.75 | RAB9A (0.47) | LMNAMAPK1HTTRAB9AKIF11 | |
| SCHEMBL27151 | 0.74 | CES2 (0.70) | LMNAMAPK1HTTRAB9ATTR | |
| SCHEMBL29349680 | 0.74 | CES2 (0.70) | LMNAMAPK1HTTRAB9ATTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595955-B1 | (4-HALOGENALKYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | BAYER IP GMBH (DE) | 2016-11-30 | — | — | EP | disclosed |
| EP-2595963-B1 | 4-(4-HALOGENALKYL-3-THIOBENZOYL)PYRAZOLES AND USE THEREOF AS HERBICIDES | BAYER IP GMBH (DE) | 2014-11-12 | — | — | EP | disclosed |
| US-8603947-B2 | (4-haloalkyl-3-thiobenzoyl)cyclohexanediones and use thereof as herbicides | BAYER CROPSCIENCE AG (DE) | 2013-12-10 | — | — | US | disclosed |
| US-8536097-B2 | 4-(4-haloalkyl-3-thiobenzoyl)pyrazoles and use thereof as herbicides | BAYER CROPSCIENCE AG (DE) | 2013-09-17 | — | — | US | disclosed |
| EP-2595955-A1 | (4-HALOGENALKYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | Bayer Intellectual Property GmbH (DE) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595963-A1 | 4-(4-HALOGENALKYL-3-THIOBENZOYL)PYRAZOLES AND USE THEREOF AS HERBICIDES | Bayer Intellectual Property GmbH (DE) | 2013-05-29 | — | — | EP | disclosed |
| US-20120021904-A1 | (4-HALOALKYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | US | disclosed |
| US-20120021903-A1 | 4-(4-HALOALKYL-3-THIOBENZOYL)PYRAZOLES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | US | disclosed |
| WO-2012010573-A1 | 4-(4-HALOGENALKYL-3-THIOBENZOYL)PYRAZOLES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010575-A1 | (4-HALOGENALKYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021904-A1 | (4-HALOALKYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | CBR3, CBR1, CYP8B1 | LMNA 4571/4885MAPK1 4127/4885HTT 774/4885 |
| US-20120021903-A1 | 4-(4-HALOALKYL-3-THIOBENZOYL)PYRAZOLES AND USE THEREOF AS HERBICIDES | CBR3, CYP4X1, PRDX4 | LMNA 4717/4885MAPK1 3767/4885HTT 556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.