SCHEMBL29623290

SCHEMBL29623290

CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCCCN)[C@@H](C)O)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ VIPR2 P41587 10/20 0.65
▸ VIPR1 P32241 7/20 0.65
▸ GLP1R P43220 3/20 0.60
▸ GHSR Q92847 2/20 0.60
▸ ECE1 P42892 1/20 0.60
▸ MUS81 Q96NY9 1/20 0.60
▸ NPY2R P49146 1/20 0.60
▸ NR3C1 P04150 3/20 0.59
▸ RAMP3 O60896 1/20 0.58
▸ CALCR P30988 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29623200 0.87 RAMP3 (0.56) VIPR2VIPR1GLP1RECE1MUS81
SCHEMBL29800212 0.87 VIPR1 (0.65) VIPR2VIPR1GLP1RECE1MUS81
SCHEMBL29412270 0.86 VIPR2 (0.66) VIPR2VIPR1GLP1RECE1MUS81
SCHEMBL29366375 0.86 VIPR2 (0.64) VIPR2VIPR1GLP1RECE1MUS81
SCHEMBL31683259 0.85 TFPI (0.64) VIPR2VIPR1
SCHEMBL29819496 0.85 IL23R (0.60) VIPR2VIPR1GLP1RNPY2R
SCHEMBL30467092 0.84 TFPI (0.62) VIPR1GLP1R
SCHEMBL34468124 0.84 TFPI (0.60) —
SCHEMBL30120636 0.84 TFPI (0.66) VIPR1GLP1RNR3C1
SCHEMBL30721553 0.84 TFPI (0.66) VIPR1GLP1RECE1MUS81NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388973-A1 MULTI-OMICS ASSESSMENT PROGNOMIQ INC (US) 2025-12-25 — — US disclosed
WO-2025227105-A1 CLEAVABLE LINKERS WITH TUNABLE HALF-LIVES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2025-10-30 — — WO disclosed
US-20240269293-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF OD THERAPEUTICS LIMITED (CN) 2024-08-15 — — US disclosed
US-20240167070-A1 METHODS FOR CYCLIZATION OF (POLY)PEPTIDES COMPRISING Ny-HYDROXY- OR Ny-AMINO-L-ASPARAGINE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2024-05-23 — — US disclosed
EP-4313154-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF OD Therapeutics Limited (HK) 2024-02-07 — — EP disclosed
US-20220401561-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF AJ SCIENCES (YIXING) CO., LTD (CN) 2022-12-22 — — US disclosed
WO-2022212362-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) 2022-10-06 — — WO disclosed
WO-2022186782-A1 METHODS FOR CYCLIZATION OF (POLY)PEPTIDES COMPRISING Nγ-HYDROXY- OR Nγ-AMINO-L-ASPARAGINE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2022-09-09 — — WO disclosed
EP-4037715-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF Beijing Xuanyi Pharmasciences Co., Ltd. (CN) 2022-08-10 — — EP disclosed
US-20220213461-A1 ASX-SPECIFIC PROTEIN LIGASES AND USES THEREOF NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2022-07-07 — — US disclosed
EP-3966321-A1 ASX-SPECIFIC PROTEIN LIGASES AND USES THEREOF Nanyang Technological University (SG) 2022-03-16 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240269293-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF CD44, MACROD1, MSN VIPR2 4130/4885VIPR1 3881/4885GLP1R 3793/4885
US-20250388973-A1 MULTI-OMICS ASSESSMENT S100A4, APOL1, SAAL1 VIPR2 4107/4885VIPR1 4096/4885GLP1R 4103/4885
US-20240167070-A1 METHODS FOR CYCLIZATION OF (POLY)PEPTIDES COMPRISING Ny-HYDROXY- OR Ny-AMINO-L-ASPARAGINE ANPEP, DNPEP, ASNS VIPR2 864/4885VIPR1 565/4885GLP1R 1151/4885
US-20220401561-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF CD44, SSB, DNPEP VIPR2 4101/4885VIPR1 3893/4885GLP1R 3651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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