SCHEMBL29366375

SCHEMBL29366375

C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ VIPR2 P41587 10/20 0.64
▸ VIPR1 P32241 7/20 0.64
▸ GLP1R P43220 3/20 0.60
▸ ECE1 P42892 1/20 0.60
▸ MUS81 Q96NY9 1/20 0.60
▸ NR3C1 P04150 4/20 0.59
▸ TFPI P10646 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Histatin 5 SCHEMBL29354282 0.93 VIPR1 (0.61) VIPR2VIPR1GLP1RECE1MUS81
Histatin 3 SCHEMBL29445556 0.90 VIPR1 (0.69) VIPR2VIPR1GLP1RECE1MUS81
SCHEMBL29581965 0.90 VIPR1 (0.55) VIPR2VIPR1GLP1RECE1MUS81
SCHEMBL30712750 0.86 VIPR2 (0.62) VIPR2VIPR1GLP1R
SCHEMBL29623290 0.86 VIPR2 (0.65) VIPR2VIPR1GLP1RECE1MUS81
SCHEMBL29777861 0.85 TFPI (0.62) VIPR2VIPR1TFPI
SCHEMBL30900782 0.84 TFPI (0.65) TFPI
SCHEMBL30900790 0.84 TFPI (0.65) TFPI
SCHEMBL29366809 0.84 OPRL1 (0.55) —
SCHEMBL31211751 0.83 TFPI (0.61) VIPR2VIPR1GLP1RTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025129271-A1 LIPID DELIVERY VEHICLE THE UNIVERSITY OF QUEENSLAND (AU) 2025-06-26 — — WO claimed
US-20240074970-A1 COMPOSITIONS FOR THE DELIVERY OF PROTEINS AFYX THERAPEUTICS A/S (DK) 2024-03-07 — — US claimed
US-20260144674-A1 Apparatus and Methods for Drug Delivery Using Microneedles CLEARSIDE BIOMEDICAL, INC. (US) 2026-05-28 — — US disclosed
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF INSTITUT CURIE (FR) 2026-05-21 — — US disclosed
US-12624002-B2 Dimers for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-05-12 — — US disclosed
US-12618031-B2 Delivery devices THE METHODIST HOSPITAL SYSTEM (US) 2026-05-05 — — US disclosed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 — — US disclosed
US-12595233-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-07 — — US disclosed
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-03-12 — — US disclosed
US-20260041746-A1 TRANSIENT EXPRESSION SYSTEM FOR RNA, FOR VACCINATION GEG TECH (FR) 2026-02-12 — — US disclosed
US-12527854-B2 Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof INSTITUT CURIE (FR) 2026-01-20 — — US disclosed
US-11440881-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-09-13 — — US disclosed
US-20220280341-A1 APPARATUS AND METHODS FOR DRUG DELIVERY USING MICRONEEDLES CLEARSIDE ROYALTY LLC 2022-09-08 — — US disclosed
US-20220280386-A1 METHODS AND APPARATUS FOR EXTRACTING FLUID FROM CONTAINER CLEARSIDE BIOMEDICAL, INC. 2022-09-08 — — US disclosed
US-11414405-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-08-16 — — US disclosed
US-20220233673-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STxB) MONOMERS AND OLIGOMERS, AND USES THEREOF INSTITUT CURIE (FR) 2022-07-28 — — US disclosed
WO-2022117764-A1 FUNCTIONALIZED SHIGA TOXIN B-SUBUNIT (STxB) PROTEINS AND CONJUGATES THEREOF INSTITUT CURIE (FR) 2022-06-09 — — WO disclosed
US-11311610-B2 Immune-modulating agents and uses therefor UNIVERSITY OF TECHNOLOGY SYDNEY (AU) 2022-04-26 — — US disclosed
CN-114126619-A Compounds for the synthesis of peptidomimetics 范因斯坦医学研究院 2022-03-01 — — CN disclosed
CN-110177527-B Device and method for adjusting insertion depth of needle for medicament delivery 科尼尔赛德生物医学公司 2022-02-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11440881-B2 Thiosemicarbazates and uses thereof TST, ABAT, AADAC VIPR2 3336/4885VIPR1 3132/4885GLP1R 557/4885
US-12624002-B2 Dimers for use in synthesis of peptidomimetics GLUL, ARGLU1, ASNS VIPR2 687/4885VIPR1 889/4885GLP1R 319/4885
US-11414405-B2 Compounds for use in synthesis of peptidomimetics DNPEP, NPEPPS, PAM VIPR2 329/4885VIPR1 502/4885GLP1R 82/4885
US-12527854-B2 Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof STXBP1, RNGTT, UPF1 VIPR2 580/4885VIPR1 949/4885GLP1R 1837/4885
US-20260144674-A1 Apparatus and Methods for Drug Delivery Using Microneedles PROKR2, SLC10A2, GLP1R VIPR2 153/4885VIPR1 321/4885GLP1R 3/4885
US-12618031-B2 Delivery devices VEGFA, PGF, CD47 VIPR2 750/4885VIPR1 696/4885GLP1R 337/4885
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS NPR1, NGLY1, DDAH1 VIPR2 684/4885VIPR1 574/4885GLP1R 116/4885
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF STXBP1, HBB, UPF1 VIPR2 501/4885VIPR1 751/4885GLP1R 1950/4885
US-12595233-B2 Thiosemicarbazates and uses thereof TST, THRB, HSPB1 VIPR2 2776/4885VIPR1 2088/4885GLP1R 139/4885
US-20260041746-A1 TRANSIENT EXPRESSION SYSTEM FOR RNA, FOR VACCINATION RNMT, NSUN2, NSUN3 VIPR2 4690/4885VIPR1 4611/4885GLP1R 4585/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT VIPR2 2819/4885VIPR1 1955/4885GLP1R 228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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