Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 2/20 | 0.54 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.54 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23045340 | 1.00 | TDO2 (0.54) | TDO2IDO2HCAR1POLBIDO1 | |
| SCHEMBL6214003 | 0.85 | TDO2 (0.57) | TDO2IDO2 | |
| SCHEMBL31419814 | 0.84 | ALDH1A1 (0.56) | TDO2IDO2POLBIDO1 | |
| SCHEMBL16345879 | 0.82 | PIK3CD (0.55) | TDO2IDO2POLBIDO1 | |
| SCHEMBL22238067 | 0.82 | POLB (0.72) | TDO2IDO2POLBIDO1 | |
| SCHEMBL9954421 | 0.82 | MEN1 (0.51) | TDO2IDO2HCAR1POLBIDO1 | |
| SCHEMBL9954457 | 0.82 | HCAR1 (0.50) | HCAR1ESR2 | |
| SCHEMBL9954657 | 0.81 | HPD (0.44) | TDO2IDO2HCAR1POLBIDO1 | |
| SCHEMBL10552036 | 0.81 | NPC1 (0.58) | HCAR1POLB | |
| SCHEMBL30103255 | 0.81 | NPC1 (0.58) | HCAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114650986-A | 2-aminoquinazolinone derivatives | 住友制药株式会社 | 2022-06-21 | — | — | CN | disclosed |