Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 2/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 2/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953129 | 0.88 | POLB (0.41) | TDO2IDO2POLBIDO1HCAR1 | |
| SCHEMBL9954457 | 0.87 | HCAR1 (0.50) | HCAR1 | |
| SCHEMBL9953665 | 0.85 | TGM2 (0.45) | HPDTGM2 | |
| SCHEMBL9954374 | 0.85 | HPD (0.44) | HPDHCAR1 | |
| SCHEMBL9953693 | 0.84 | LMNA (0.47) | — | |
| SCHEMBL9954100 | 0.83 | SMN1; SMN2 (0.55) | HPDPOLB | |
| SCHEMBL9954749 | 0.82 | PDE7A (0.45) | HCAR1 | |
| SCHEMBL9954549 | 0.82 | MAT2A (0.43) | — | |
| SCHEMBL23045340 | 0.81 | TDO2 (0.54) | TDO2IDO2POLBIDO1HCAR1 | |
| SCHEMBL29623384 | 0.81 | TDO2 (0.54) | TDO2IDO2POLBIDO1HCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |