Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 3/20 | 0.51 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.47 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22804720 | 1.00 | PLOD2 (0.51) | PLOD2PLOD3PLOD1EPHX2ALDH1A1 | |
| SCHEMBL29623556 | 0.84 | PLOD2 (0.51) | PLOD2PLOD3PLOD1ALDH1A1L3MBTL1 | |
| SCHEMBL22804819 | 0.84 | PLOD2 (0.51) | PLOD2PLOD3PLOD1ALDH1A1L3MBTL1 | |
| SCHEMBL22804475 | 0.83 | PLOD2 (0.60) | PLOD2PLOD3PLOD1ALDH1A1LMNA | |
| SCHEMBL7839202 | 0.80 | ALDH1A1 (0.52) | EPHX2ALDH1A1LMNABLMNPSR1 | |
| SCHEMBL365542 | 0.75 | PKM (0.49) | EPHX2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL584065 | 0.74 | PLOD2 (0.70) | PLOD2PLOD3PLOD1ALDH1A1LMNA | |
| SCHEMBL523476 | 0.74 | PLOD2 (0.69) | PLOD2PLOD3PLOD1ALDH1A1LMNA | |
| SCHEMBL13239476 | 0.73 | HPGD (0.62) | EPHX2ALDH1A1LMNABLMNPSR1 | |
| SCHEMBL4032443 | 0.73 | PLOD2 (0.64) | PLOD2PLOD3PLOD1EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986875-A1 | PHENOXYPHENYL HYDROXYISOXAZOLINES AND ANALOGUES AS NEW ANTIFUNGAL AGENTS | Bayer Aktiengesellschaft (DE) | 2022-04-27 | — | — | EP | disclosed |