Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | USP7 | Q93009 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365542 | 0.84 | PKM (0.49) | HPGDALDH1A1MAPTEPHX2PKM | |
| SCHEMBL5830744 | 0.81 | MAPT (0.48) | HPGDALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL13239474 | 0.81 | HPGD (0.65) | HPGDALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL5326846 | 0.80 | HPGD (0.56) | HPGDALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL7839202 | 0.80 | ALDH1A1 (0.52) | HPGDALDH1A1LMNAMAPTEPHX2 | |
| SCHEMBL20591215 | 0.79 | HPGD (0.62) | HPGDALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL11554461 | 0.79 | ALDH1A1 (0.62) | HPGDALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL2557767 | 0.78 | HPGD (0.66) | HPGDALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL194744 | 0.77 | HPGD (1.00) | HPGDALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL10870776 | 0.77 | HPGD (1.00) | HPGDALDH1A1LMNAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11427536-B2 | Photocatalyst-free, light-induced carbon-sulfur cross-coupling methods | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2022-08-30 | — | — | US | disclosed |
| US-20180370911-A1 | PHOTOCATALYST-FREE, LIGHT-INDUCED CARBON-SULFUR CROSS-COUPLING METHODS | U.S. DEPARTMENT OF ENERGY | 2018-12-27 | — | — | US | disclosed |
| US-7754890-B2 | Arylsulfones and uses related thereto | AMGEN INC. (US) | 2010-07-13 | — | — | US | disclosed |
| US-7754890-B2 | Arylsulfones and uses related thereto | AMGEN INC. (US) | 2010-07-13 | — | — | US | disclosed |
| US-20080269283-A1 | ARYLSULFONES AND USES RELATED THERETO | AMGEN INC. | 2008-10-30 | — | — | US | disclosed |
| US-20080269283-A1 | ARYLSULFONES AND USES RELATED THERETO | AMGEN INC. | 2008-10-30 | — | — | US | disclosed |
| US-7402704-B2 | Arylsulfones and uses related thereto | AMGEN INC. (US) | 2008-07-22 | — | — | US | disclosed |
| US-7402704-B2 | Arylsulfones and uses related thereto | AMGEN INC. (US) | 2008-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180370911-A1 | PHOTOCATALYST-FREE, LIGHT-INDUCED CARBON-SULFUR CROSS-COUPLING METHODS | TST, CBS, CRY2 | HPGD 1394/4885ALDH1A1 716/4885LMNA 4215/4885 |
| US-20080269283-A1 | ARYLSULFONES AND USES RELATED THERETO | ARSA, SULT2A1, UGT2B7 | HPGD 1892/4885ALDH1A1 128/4885LMNA 4072/4885 |
| US-11427536-B2 | Photocatalyst-free, light-induced carbon-sulfur cross-coupling methods | TST, CBS, CRY2 | HPGD 1394/4885ALDH1A1 716/4885LMNA 4215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.