SCHEMBL29627465

SCHEMBL29627465

O=c1ccoc2c1ccc1ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.54
KDM4E B2RXH2 5/20 0.54
HTT P42858 4/20 0.54
KMT2A Q03164 3/20 0.54
POLB P06746 2/20 0.54
ESR1 P03372 1/20 0.54
MAPT P10636 4/20 0.53
PAX8 Q06710 2/20 0.53
MAOA P21397 1/20 0.52
MAOB P27338 1/20 0.52
FTO Q9C0B1 1/20 0.52
CYP1A1 P04798 7/20 0.50
CYP1B1 Q16678 7/20 0.50
CYP1A2 P05177 6/20 0.50
HPGD P15428 5/20 0.50
MEN1 O00255 2/20 0.50
HSD17B10 Q99714 2/20 0.50
PRKDC P78527 2/20 0.50
LMNA P02545 1/20 0.50
ALOX15 P16050 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3617428 1.00 ALDH1A1 (0.54) ALDH1A1KDM4EHTTKMT2APOLB
SCHEMBL29025751 0.93 PAX8 (0.57) ALDH1A1KDM4EHTTKMT2APOLB
SCHEMBL3584109 0.79 ALDH1A1 (0.49) ALDH1A1KDM4EHTTKMT2APOLB
SCHEMBL8563087 0.77 ALDH1A1 (0.50) ALDH1A1KDM4EHTTKMT2APOLB
SCHEMBL29853219 0.77 ALDH1A1 (0.50) ALDH1A1KDM4EHTTKMT2APOLB
SCHEMBL28174357 0.75 ALDH1A1 (0.55) ALDH1A1KDM4EHTTKMT2APOLB
SCHEMBL28763218 0.74 HPRT1 (0.44) ALDH1A1KDM4EHTTKMT2APOLB
SCHEMBL31360532 0.74 HPRT1 (0.44) ALDH1A1KDM4EHTTKMT2APOLB
SCHEMBL11350264 0.74 LMNA (0.47) ALDH1A1KDM4EHTTKMT2APOLB
SCHEMBL13167563 0.73 CYP1A1 (0.43) ALDH1A1KDM4EHTTKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 WO disclosed
CN-114560837-B Chromone compound and preparation method and application thereof 五邑大学 2023-11-24 CN disclosed
CN-114560837-A Chromone compound and preparation method and application thereof 五邑大学 2022-05-31 CN disclosed